Valsartan (CAS: 137862-53-4) An In-Depth Review of a Powerful Pharmaceutical Compound

Introduction:

In the world of pharmaceuticals, few compounds have gained as much recognition as Valsartan (CAS: 137862-53-4). This article aims to provide a comprehensive overview of this product, including its chemical properties, health benefits, potential effects, safety profile, dosing information, and more. Let's dive into the details.

Chemical Name, Molecular Formula, Formula Weight, and CAS Number:

Valsartan's chemical name is (s)-3-methyl-2-(N-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]pentanamido)butanoic acid. Its molecular formula is C24H29N5O3, and the formula weight is 435.52 g/mol. The compound is identified by CAS number 137862-53-4.

Top Ten Keywords and Synonyms:

After conducting extensive research, we have compiled the top ten keywords associated with Valsartan: hypertension, angiotensin receptor blocker, cardiovascular health, blood pressure, antihypertensive, ARB, heart disease, hypertension treatment, renin-angiotensin-aldosterone system, and hypertension medication. Synonyms vary but may include Diovan, Tareg, Valtan, and Valzaar.

Similar Competitive Products:

Within the class of angiotensin receptor blockers (ARBs), Valsartan competes with other well-known compounds such as Losartan, Irbesartan, Candesartan, and Olmesartan. These medications present similar therapeutic effects in managing hypertension and cardiac conditions.

Health Benefits:

Valsartan is primarily prescribed to manage hypertension (high blood pressure), a common condition affecting a significant portion of the global population. By blocking the angiotensin II receptors, Valsartan helps relax the blood vessels, reducing resistance and thus lowering blood pressure. Additionally, it provides cardiovascular benefits, preventing heart attacks, strokes, and related complications.

Potential Effects:

When used as advised by a healthcare professional, Valsartan exhibits a range of potential effects. It helps maintain healthy blood pressure levels, reducing strain on the heart and maintaining proper organ function. By doing so, it may lower the risk of developing heart disease, heart failure, and other cardiovascular complications.

Product Mechanism:

Valsartan's main mechanism of action involves selectively blocking the angiotensin II type 1 receptors, preventing them from binding to angiotensin II. This inhibits the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to vasodilation, increased sodium excretion, and reduced blood pressure.

Safety and Side Effects:

Valsartan is generally well-tolerated, but like any medication, it may have side effects. Common ones include dizziness, fatigue, hypotension, headache, gastrointestinal disturbances, and a dry or persistent cough. It is important to consult a healthcare professional for advice on possible interindividual differences or interactions with other medications.

Dosing Information:

The dosing of Valsartan should be determined and adjusted by a healthcare professional based on individual patient needs. Typically, a starting dose of 80 mg once daily is recommended. Depending on the response, the dose may be increased up to 320 mg daily. Patients with certain medical conditions or taking specific medications may require personalized dosing regimens.

Contraindications:

Valsartan is contraindicated in patients with known hypersensitivity to the drug or other ARBs. Special caution is advised in individuals with severe liver or kidney disease, as well as during pregnancy and breastfeeding, where alternative treatments should be considered.

Conclusion:

Valsartan (CAS: 137862-53-4) is a potent pharmaceutical compound belonging to the category of angiotensin receptor blockers. It offers a range of health benefits, particularly in managing hypertension and reducing the risk of cardiovascular complications. While it is generally safe and well-tolerated, it is crucial to consult with a healthcare professional for personalized dosing and monitoring. With its remarkable therapeutic properties, Valsartan continues to play a crucial role in improving the lives of those affected by hypertension and related conditions