ADL5859 hydrochloride is a selective agonist of the delta-opioid receptor, which plays a key role in pain modulation and reward mechanisms. It has potential applications in the treatment of chronic pain, depression, anxiety, and addiction.
Chemical name: methyl (2S)-2-[(5R,9R)-9-(4-chlorophenyl)-5-(3,3-dimethylbut-1-yn-1-yl)-13-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]acetate hydrochloride
Molecular formula: C28H30ClNO3.HCl
Formula weight: 522.01 g/mol
CAS No: 850173-95-4
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Health benefits of this product: ADL5859 has been shown to have potent analgesic effects in animal models of chronic pain, both alone and in combination with other pain-relieving drugs. It may also have potential applications in the treatment of depression, anxiety, and addiction.
Potential effects: As a selective delta-opioid receptor agonist, ADL5859 has the potential to relieve chronic pain and improve symptoms of depression, anxiety, and addiction. It may also have fewer side effects than traditional opioid analgesics, such as respiratory depression and addiction. However, more research is needed to fully understand the potential effects of ADL5859.
Product mechanism: ADL5859 works by binding selectively to the delta-opioid receptor, which plays a key role in pain modulation and reward mechanisms. Activation of this receptor leads to a reduction in pain sensations and an increase in feelings of well-being and pleasure.
Safety: ADL5859 has been shown to be generally safe in preclinical studies, but like all drugs, it can cause side effects. Patients should consult their healthcare provider before beginning treatment with ADL5859 to discuss any potential risks or concerns.
Side effects: The most common side effects of ADL5859 in preclinical studies were mild gastrointestinal upset and sedation. Other potential side effects may include dizziness, headache, and impaired motor function. Patients should report any severe or persistent side effects to their healthcare provider.
Dosing information: ADL5859 dosing varies depending on the indication and patient factors such as age, weight, and overall health. It is typically administered orally or intravenously. Patients should follow their healthcare provider's dosing instructions carefully and report any missed doses or changes in symptoms.
Conclusion: ADL5859 hydrochloride is a promising drug candidate for the treatment of chronic pain, depression, anxiety, and addiction. Its ability to selectively activate the delta-opioid receptor makes it a potentially valuable tool in pain modulation and reward mechanisms. However, like all drugs, it can cause side effects, and patients should be aware of the potential risks and consult their healthcare provider before beginning treatment with ADL5859.
