Alfacalcidol is a synthetic analog of vitamin D that is used to treat various conditions related to calcium and bone metabolism. It was first discovered in 1972 and has since been studied for its therapeutic potential.
Chemical name:
The chemical name for alfacalcidol is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1α,3β-diol.
Molecular formula:
The molecular formula of alfacalcidol is C27H44O2.
Formula weight:
The formula weight of alfacalcidol is 400.64 g/mol.
CAS No:
The CAS number of alfacalcidol is 41294-56-8.
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Synonyms:
Health benefits of this product:
Alfacalcidol is primarily used to treat various conditions related to calcium and bone metabolism, including osteoporosis, renal osteodystrophy, and hypoparathyroidism. It may also be used to prevent and treat vitamin D deficiency.
Potential effects:
Some potential effects of alfacalcidol include:
Product mechanism:
Alfacalcidol works by binding to and activating the vitamin D receptor, which is present on cells in various organs throughout the body. Activation of the vitamin D receptor leads to increased absorption of calcium from the intestines, increased reabsorption of calcium from the kidneys, and increased bone resorption.
Safety:
Alfacalcidol has been tested in multiple clinical studies for its safety profile. The drug has been found to have a favorable safety profile and has not shown any significant adverse effects on normal tissues or organs. However, as with any medication, there are some risks associated with its use. Patients should inform their healthcare provider of any pre-existing medical conditions or medications they are taking before starting treatment with alfacalcidol.
Side effects:
Alfacalcidol can cause several side effects in some patients. These can include:
Dosing information:
The optimal dosing regimen of alfacalcidol depends on the condition being treated, patient age and weight, and other factors. In general, doses range from 0.25 mcg to 1.5 mcg once daily. The drug is typically administered orally.
Conclusion:
Alfacalcidol is a synthetic analog of vitamin D that is used to treat various conditions related to calcium and bone metabolism. By binding to and activating the vitamin D receptor, alfacalcidol may increase calcium absorption, decrease calcium excretion, and improve bone density and mineral content. The drug has undergone multiple clinical trials and has been found to have a favorable safety profile. However, as with any medication, there are some risks associated with its use. Further research is needed to determine the optimal dosing regimen and efficacy of alfacalcidol in treating various conditions related to calcium and bone metabolism