Apigenin, also known as 4',5,7-trihydroxyflavone, is a naturally occurring flavonoid that is found in many plant-based foods. It has been researched for its potential health benefits, including its anti-inflammatory, antioxidant, and anticancer properties. Apigenin's chemical name is 5,7-dihydroxy-2-(4-hydroxyphenyl) chromen-4-one. Its molecular formula is C15H10O5, and its formula weight is 270.24 g/mol. Its CAS No is 520-36-5.
Top Ten Keywords: Apigenin, flavonoid, anti-inflammatory, antioxidant, anticancer, natural product, apoptosis, cell growth, plant-based, clinical trials.
Synonyms: 4',5,7-trihydroxyflavone, CAS 520-36-5.
Health Benefits of Apigenin: Apigenin has been researched for its potential health benefits. It has been shown to have anti-inflammatory and antioxidant effects, making it a potential treatment for conditions related to oxidative stress and chronic inflammation, such as cardiovascular disease and neurodegenerative diseases. Additionally, apigenin has been found to have anticancer properties and may be effective in preventing the growth and spread of cancer cells.
Potential Effects: Some of the potential effects of apigenin include its ability to inhibit the growth of cancer cells, promote apoptosis or programmed cell death, and reduce inflammation. It has also been shown to have antioxidant effects and may be useful in preventing oxidative stress-related disorders such as cardiovascular disease and neurodegenerative diseases. Additionally, apigenin has been found to have potential beneficial effects on memory and cognitive function.
Product Mechanism: Apigenin exerts its effects by regulating various cellular signaling pathways. It can inhibit enzyme activity that is necessary for cancer cell growth and proliferation, leading to the activation of apoptotic pathways. Additionally, apigenin can modulate various transcription factors and cytokines that are involved in inflammation, reducing inflammation and oxidative stress.
Safety: Apigenin has been found to be generally safe when consumed in dietary amounts. However, high doses of apigenin may cause toxicity or adverse side effects. Further research is necessary to determine the safety of apigenin at high doses.
Side Effects: The side effects of apigenin are generally mild, with few reports of adverse reactions. However, some studies have indicated that high doses of apigenin may be toxic and lead to adverse effects such as liver damage or oxidative stress.
Dosing Information: Dosing information for apigenin varies depending on the condition being treated and the patient. Apigenin is found in many plant-based foods and is also available as a dietary supplement. However, it is essential to consult a healthcare provider before taking any supplements or herbs.
In conclusion, apigenin is a promising natural product that has demonstrated potential health benefits, including anti-inflammatory, antioxidant, and anticancer effects. Its mechanism of action involves modulating various cellular signaling pathways that regulate the growth, survival, and proliferation of cells. While generally safe, high doses of apigenin may be toxic and lead to adverse effects such as liver damage or oxidative stress. Further research is necessary to determine its efficacy and safety in the treatment of various conditions. Apigenin represents a potential alternative to traditional pharmaceuticals for the treatment of inflammation, cancer, and other oxidative stress-related conditions.