Azilsartan (CAS: 147403-03-0) is a medication that belongs to the class of angiotensin II receptor blockers (ARBs). It is used to treat hypertension, or high blood pressure, by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict and blood pressure to rise.
Chemical name: 2-Ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
Molecular formula: C25H20N4O5
Formula weight: 444.45 g/mol
CAS No: 147403-03-0
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Health benefits of this product: Azilsartan has demonstrated potential health benefits in several areas, particularly in the treatment of hypertension and cardiovascular disease. It may also have potential benefits for renal protection and stroke prevention, although more research is needed in these areas.
Potential effects: Azilsartan has demonstrated efficacy in several preclinical and clinical studies in reducing blood pressure, improving arterial stiffness, and preventing cardiovascular events in patients with hypertension. It also has potential benefits for renal protection and stroke prevention. Azilsartan works by selectively blocking the angiotensin II receptor, leading to relaxation of blood vessels and reduced blood pressure.
Product mechanism: Azilsartan works by selectively blocking the angiotensin II receptor, which is responsible for causing blood vessels to constrict and blood pressure to rise. By blocking this receptor, azilsartan leads to relaxation of blood vessels, increased blood flow, and reduced blood pressure. It also has potential benefits for reducing inflammation and oxidative stress in the cardiovascular system.
Safety: Azilsartan has been evaluated in several clinical trials involving thousands of participants and has been generally well-tolerated. Rare but potential side effects may include dizziness, headache, diarrhea, and allergic reactions. Patients with kidney disease or liver disease should exercise caution when taking azilsartan, as it may affect these conditions. Pregnant or breastfeeding women should avoid using azilsartan, as it may cause harm to the developing fetus or infant.
Side effects: Common side effects of azilsartan may include dizziness, headache, diarrhea, and fatigue. These symptoms are usually mild or moderate and can be managed with supportive care or dose modifications. Less common but more severe side effects may include hyperkalemia (high potassium levels), hypotension (low blood pressure), and renal impairment, which may require prompt medical intervention. Patients should be monitored closely for these adverse events and receive appropriate medical intervention if necessary.
Dosing information: The optimal dose and dosing regimen of azilsartan may vary depending on the patient's condition and treatment goals. In clinical trials, doses ranging from 20 to 80 mg per day have been evaluated for hypertension. Patients should follow their doctor's instructions regarding dosing, administration, and monitoring.
Conclusion: Azilsartan (CAS: 147403-03-0) is a medication that belongs to the class of angiotensin II receptor blockers (ARBs) that is used to treat hypertension and prevent cardiovascular events. It works by selectively blocking the angiotensin II receptor, leading to relaxation of blood vessels and reduced blood pressure. Although it has been generally well-tolerated, it may cause some side effects that should be monitored closely. More research is needed to determine its full potential and efficacy in different patient populations and its long-term safety profile
