Azilsartan medoxomil, also known as TAK-491, is a medication used to treat high blood pressure. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs) and works by blocking the action of the hormone angiotensin II, which can cause blood vessels to narrow and increase blood pressure. Its chemical name is 2-Ethoxy-1-[[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid methyl ester cyclohexylamine salt, and its molecular formula is C30H34N6O4•C4H11N, with a formula weight of 626.80 g/mol. The CAS number for azilsartan medoxomil is 863031-21-4.
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Some synonyms for azilsartan medoxomil include TAK-491, Edarbi, and AZL-M.
Health Benefits of Azilsartan Medoxomil
Azilsartan medoxomil is primarily used to lower high blood pressure, which can reduce the risk of heart attack, stroke, and other cardiovascular complications. Additionally, it may help improve kidney function in patients with diabetes.
Potential Effects of Azilsartan Medoxomil
In addition to its blood pressure-lowering effects, azilsartan medoxomil may have other potential benefits for certain populations. For example, it may help improve endothelial function in patients with metabolic syndrome. It may also have a protective effect on the heart and kidneys, especially in patients with chronic kidney disease.
Product Mechanism
Azilsartan medoxomil works by blocking the action of the hormone angiotensin II, which can cause blood vessels to narrow and increase blood pressure. By blocking this action, azilsartan medoxomil helps dilate blood vessels, which can lower blood pressure and reduce the workload on the heart.
Safety
Azilsartan medoxomil is generally considered safe when used as directed. However, it should not be used during pregnancy, and women who are pregnant or planning to become pregnant should talk to their healthcare provider about alternative blood pressure medications. Additionally, azilsartan medoxomil may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) and diuretics. Patients should always talk to their healthcare provider about any concerns or potential interactions.
Side Effects
Common side effects of azilsartan medoxomil include dizziness, headache, and back pain. Less common but more serious side effects may include allergic reactions, kidney problems, and low blood pressure. Patients should talk to their healthcare provider about any side effects experienced while taking azilsartan medoxomil.
Dosing Information
The dosing information for azilsartan medoxomil may vary depending on individual needs and medical history. It is important to follow dosing instructions carefully and take the medication at the same time every day. Patients should never adjust their dose without first talking to their healthcare provider.
Conclusion
Azilsartan medoxomil is a medication used to treat high blood pressure by blocking the action of the hormone angiotensin II. While it is generally considered safe when used as directed, it may interact with other medications and should not be used during pregnancy. In addition to its blood pressure-lowering effects, azilsartan medoxomil may have other potential benefits, such as improving endothelial function and protecting the heart and kidneys. As with any medication, patients should talk to their healthcare provider about any concerns or potential side effects
