Candesartan Cilexetil CAS: 145040-37-5 is a prescription medication used to treat hypertension (high blood pressure). It belongs to the class of drugs known as angiotensin II receptor blockers (ARBs) and works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow and raises blood pressure.
Chemical Name: (±)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester-2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate Molecular Formula: C33H34N6O6 Formula Weight: 610.65 g/mol CAS No: 145040-37-5
Top ten keywords from Google related to Candesartan Cilexetil are: high blood pressure, hypertension, ARBs, angiotensin II receptor blockers, heart failure, stroke, kidney disease, cardiovascular disease, blood pressure lowering drugs, and antihypertensive medication.
Synonyms for Candesartan Cilexetil include Atacand, Blopress, Amias, and Kenzen.
Health Benefits: Candesartan Cilexetil is primarily used to lower blood pressure in patients with hypertension. It can also be prescribed to treat heart failure and reduce the risk of stroke in patients with left ventricular systolic dysfunction. Additionally, it may help delay the progression of kidney disease in patients with type 2 diabetes who have proteinuria.
Potential Effects: Candesartan Cilexetil blocks the action of angiotensin II, which causes blood vessels to constrict and raises blood pressure. By dilating blood vessels, it lowers blood pressure, reduces the workload on the heart, and increases blood flow to the kidneys. This can help reduce the risk of stroke, heart attack, and kidney damage.
Product Mechanism: Candesartan Cilexetil works by selectively blocking the binding of angiotensin II to its receptors in blood vessels and other tissues, including the heart and kidneys. This results in the relaxation and dilation of blood vessels, which lowers blood pressure and improves blood flow to vital organs.
Safety: Candesartan Cilexetil is generally considered safe when taken as directed by a healthcare professional. However, like all medications, it may cause side effects, interactions, and allergic reactions. Patients should inform their doctor of any medical conditions they have, medications they are taking, or allergies they have before starting treatment with Candesartan Cilexetil.
Side Effects: Some common side effects of Candesartan Cilexetil include dizziness, headache, fatigue, nausea, vomiting, diarrhea, cough, and back pain. Less common but more serious side effects may include allergic reactions, low blood pressure, kidney problems, liver problems, and electrolyte imbalances.
Dosing Information: The recommended dose of Candesartan Cilexetil for hypertension is usually 16-32 mg once daily. The maximum dose is 32 mg/day. For heart failure and left ventricular systolic dysfunction, the recommended starting dose is 4 mg once daily, which may be increased to 32 mg once daily over several weeks. In patients with kidney impairment, the dose may need to be adjusted based on the severity of the condition.
In conclusion, Candesartan Cilexetil is an effective medication for treating hypertension, heart failure, and reducing the risk of stroke. It works by blocking the action of angiotensin II, a hormone that raises blood pressure. While generally safe, it may cause side effects and interact with other medications, so patients should always consult with a healthcare professional before starting treatment