Droxinostat, also known as NS41080 or NS-41080 CAS: 99873-43-5, is a chemical compound that has shown promise in the treatment of various diseases. This product is primarily known for its ability to inhibit histone deacetylases (HDACs), which play a critical role in gene expression and various cellular processes. In this article, we will explore the chemical properties of Droxinostat, its potential health benefits, safety considerations, and dosing information.
Chemical name:
The chemical name for Droxinostat is N-hydroxy-4-(2-methoxy-6-phenylamino-pyrimidin-4-yl)-butanamide.
Molecular formula:
The molecular formula of Droxinostat is C16H18N4O3.
Formula weight:
The molecular weight of Droxinostat is 310.34 g/mol.
CAS No:
The CAS number for Droxinostat is 99873-43-5.
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Health benefits of this product:
Droxinostat has been found to have a variety of potential health benefits. One of the most studied applications of this compound is in the treatment of cancer. Specifically, Droxinostat may be effective in treating lymphoma, lung cancer, and breast cancer. Studies have shown that Droxinostat can inhibit the growth of cancer cells by blocking the activity of HDACs, which play a critical role in regulating gene expression and various cellular processes.
In addition to cancer treatment, Droxinostat may also have potential in the treatment of other diseases related to epigenetics, inflammation, and cellular differentiation. These conditions include autoimmune diseases, neurodegenerative disorders, and cardiovascular disease.
Potential effects:
Droxinostat works by inhibiting the activity of HDAC enzymes. HDAC enzymes play an important role in gene expression, cellular differentiation, and apoptosis. By inhibiting these enzymes, Droxinostat may be able to influence these processes and potentially affect the development and progression of various diseases.
Product mechanism:
The precise mechanism of action of Droxinostat is not well understood, but it is believed to work by binding to and inhibiting the activity of HDAC enzymes.
Safety:
Droxinostat is generally considered to be safe when used as directed. However, as with any medication or supplement, there is some risk of side effects. It is important to consult with a healthcare provider before using Droxinostat, especially if you have any underlying medical conditions or are taking other medications.
Side effects:
Some potential side effects of Droxinostat include nausea, vomiting, fatigue, and diarrhea. More serious side effects may include liver toxicity and blood disorders. If you experience any of these symptoms or other severe side effects, you should seek medical attention immediately.
Dosing information:
The optimal dosage of Droxinostat will depend on the specific application and the individual's needs. It is important to follow the dosing instructions provided by a healthcare provider or on the product label. In general, doses of Droxinostat in the range of 30-60 mg/kg per day have been used in animal studies.
Conclusion:
Droxinostat is a promising compound with potential health benefits in the treatment of cancer and other diseases related to epigenetics, inflammation, and cellular differentiation. Its mechanism of action through the inhibition of HDAC enzymes is a promising avenue for new drug therapies. While generally safe, it is important to consult with a healthcare provider before using Droxinostat and to follow dosing instructions carefully. Further research is needed to fully understand the potential benefits and risks of this compound
