Duloxetine Hydrochloride, also known as Cymbalta, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and chronic pain. It belongs to the class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which work by increasing the levels of these neurotransmitters in the brain.
The chemical name of Duloxetine Hydrochloride is (+)-(S)-N-Methyl-3-(1-naphthyloxy)-2-thiophenepropanamine hydrochloride.
The molecular formula of Duloxetine Hydrochloride is C18H20ClNOS.
The formula weight of Duloxetine Hydrochloride is 333.88 g/mol.
The CAS number of Duloxetine Hydrochloride is 136434-34-9.
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Synonyms: Duloxetine, Duloxetine HCl, Ariclaim, Duzela, Yentreve
Health Benefits of Duloxetine Hydrochloride:
Duloxetine Hydrochloride is primarily used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and chronic pain. It helps in reducing symptoms such as low mood, loss of interest, anxiety, and pain. Additionally, it can improve energy level and quality of life in some patients.
Duloxetine Hydrochloride is an SNRI that works by increasing the levels of serotonin and norepinephrine in the brain. By doing so, it improves the communication between neurons and enhances mood, reduces anxiety, and alleviates pain. It also has a sedative effect, which can help patients sleep better.
Duloxetine Hydrochloride works by inhibiting the reuptake of serotonin and norepinephrine in the brain. These neurotransmitters are responsible for regulating mood, anxiety, and pain perception. By blocking their reuptake, Duloxetine Hydrochloride increases their availability in the synaptic cleft, which enhances their effects and leads to improved mood, reduced anxiety, and pain relief.
Duloxetine Hydrochloride is generally considered safe when used as directed. However, like all medications, it may cause side effects in some people. It is not recommended for certain patients, such as those who have liver disease, severe renal impairment, or a history of suicidal ideation. It should also be used with caution in people with glaucoma, bipolar disorder, or a bleeding disorder.
Common side effects of Duloxetine Hydrochloride include nausea, dry mouth, constipation, and insomnia. Rare but serious side effects may include serotonin syndrome, hyponatremia, and hepatotoxicity. Patients who experience any of these symptoms should seek immediate medical attention.
The recommended dose of Duloxetine Hydrochloride depends on the condition being treated and the individual patient's response to the medication. For major depressive disorder, the usual starting dose is 60 mg once daily, which may be increased gradually to a maximum of 120 mg per day. For generalized anxiety disorder, the recommended starting dose is 30 mg once daily, which may be increased gradually to a maximum of 120 mg per day. For fibromyalgia and chronic pain, the usual dose is 60 mg once daily, and may be increased to 120 mg per day if needed.
Duloxetine Hydrochloride is an SNRI medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and chronic pain. It works by increasing the levels of serotonin and norepinephrine in the brain, which can improve mood, reduce anxiety, and alleviate pain. While it is generally safe and effective, it may cause side effects in some patients and is not recommended for certain populations. If you have any questions about Duloxetine Hydrochloride or its use, please consult your healthcare provider