EGC, also known as (-)-Epigallocatechin, is a type of catechin that is commonly found in tea. This product has been studied for its potential health benefits, particularly in cardiovascular health, cognitive function, and cancer prevention. In this article, we will discuss the chemical properties, health benefits, potential effects, mechanism, safety, side effects, dosing information, and conclusion of EGC.
Chemical Properties The chemical name of EGC is (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol. Its molecular formula is C15H14O7, and its formula weight is 306.27 g/mol. The CAS number of EGC is 970-74-1.
Top Ten Keywords and Synonyms
- Cardiovascular health
- Cognitive function
- Cancer prevention
- Green tea
- Epicatechin gallate
- Gallocatechin gallate
- (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3-chromenecarboxylic acid
- (−)-Epigallocatechin gallate
- Epigallocatechol gallate
- Epigallocatechin 3-O-gallate
Health Benefits Studies have suggested several potential health benefits of EGC. One of the most significant benefits is its potential to improve cardiovascular health by reducing blood pressure, improving arterial function, and decreasing the risk of heart disease. Additionally, EGC has been studied for its potential neuroprotective effects, improving cognitive function and reducing the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's.
EGC is believed to act as an antioxidant, protecting cells from oxidative stress and reducing inflammation throughout the body. Furthermore, it may contribute to cancer prevention by inhibiting tumor growth and inducing apoptosis, or programmed cell death, in cancer cells.
Potential Effects EGC has a range of potential effects on the body, including regulating lipid metabolism, improving insulin sensitivity, reducing inflammation, and enhancing mitochondrial biogenesis. It may also promote healthy gut microbiota and improve immune function.
Product Mechanism The health benefits of EGC are believed to be due to its ability to modulate several pathways within the body. For example, it may activate the nitric oxide pathway, which helps to relax blood vessels, leading to improved blood flow and reduced blood pressure. It may also inhibit cancer cell proliferation by inducing apoptosis and suppressing tumor angiogenesis.
Safety and Side Effects EGC appears to be safe when consumed in moderate amounts found in food sources such as green tea. However, taking high doses of EGC supplements may cause adverse effects such as gastrointestinal distress, headaches, and dizziness. It is always recommended to consult with a healthcare provider before taking any new supplement.
Dosing Information There is no established dose of EGC, but studies have used doses ranging from 50 mg to 800 mg per day. It is best to start with a lower dose and gradually increase as needed.
Conclusion EGC is a type of catechin commonly found in tea that has numerous potential health benefits, particularly in cardiovascular health, cognitive function, and cancer prevention. While it appears to be safe when consumed in moderate amounts, taking high doses of EGC supplements may cause adverse effects. If you are interested in taking EGC supplements, it is recommended to consult with a healthcare provider to determine the appropriate dosage and ensure safety