Forskolin (CAS: 66575-29-9) is a natural compound that is derived from the roots of the Indian Coleus plant (Plectranthus barbatus). It has been traditionally used in Ayurvedic medicine for various conditions, such as asthma and heart disease. Forskolin has been extensively studied for its potential health benefits, particularly in the areas of weight loss, cardiovascular health, and respiratory health.
Chemical name: 7beta-acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one
Molecular formula: C22H34O7
Formula weight: 410.50 g/mol
CAS No: 66575-29-9
Top ten keywords from Google:
Synonyms:
Health benefits of this product: Forskolin has demonstrated potential health benefits in several areas, including weight loss, cardiovascular health, and respiratory health. It works by activating the enzyme adenylate cyclase, which increases the production of cyclic AMP (cAMP), a molecule that regulates various physiological processes, such as metabolism, blood pressure, and inflammation. Forskolin may also have potential benefits for skin health, digestive health, and cancer prevention, although more research is needed in these areas.
Potential effects: Forskolin has demonstrated efficacy in several preclinical and clinical studies in promoting weight loss, reducing blood pressure, improving respiratory function, and reducing inflammation. It may also have potential benefits for skin health, digestive health, and cancer prevention. Forskolin works by activating adenylate cyclase, which increases the production of cAMP and activates various signaling pathways in the body.
Product mechanism: Forskolin works by activating adenylate cyclase, an enzyme that catalyzes the conversion of ATP to cAMP. cAMP is a molecule that regulates various physiological processes, such as metabolism, blood pressure, and inflammation. When cAMP levels increase, it activates various signaling pathways in the body, leading to a range of beneficial effects. Forskolin specifically activates adenylate cyclase in adipose tissue, leading to increased lipolysis (fat breakdown) and weight loss.
Safety: Forskolin has been evaluated in several clinical trials involving hundreds of participants and has been generally well-tolerated. Rare but potential side effects may include headache, dizziness, and gastrointestinal symptoms. Patients with low blood pressure or bleeding disorders should exercise caution when taking forskolin, as it may affect these conditions. Pregnant or breastfeeding women should avoid using forskolin, as its safety in these populations has not been established.
Side effects: Common side effects of forskolin may include headache, dizziness, and gastrointestinal symptoms, such as nausea, diarrhea, and stomach pain. These symptoms are usually mild or moderate and can be managed with supportive care or dose modifications. Less common but more severe side effects may include hypotension or bleeding disorders, which may require prompt medical intervention. Patients should be monitored closely for these adverse events and receive appropriate medical intervention if necessary.
Dosing information: The optimal dose and dosing regimen of forskolin may vary depending on the patient's condition and treatment goals. In clinical trials, doses ranging from 125 to 250 mg of standardized extract (10-20% forskolin) per day have been evaluated for weight loss and cardiovascular health. For respiratory health, doses ranging from 10 to 40 mg of forskolin per day have been evaluated. Patients should follow their doctor's instructions regarding dosing, administration, and monitoring.
Conclusion: Forskolin (CAS: 66575-29-9) is a natural compound derived from the roots of the Indian Coleus plant that has been traditionally used in Ayurvedic medicine for various conditions. It has demonstrated potential health benefits in several areas, including weight loss, cardiovascular health, and respiratory health. Forskolin works by activating adenylate cyclase, leading to increased production of cAMP and activation of various signaling pathways in the body. Although it has been generally well-tolerated, it may cause some side effects that should be monitored closely. More research is needed to determine its full potential and efficacy in different patient populations and its long-term safety profile
