Go6976 Go-6976 CAS: 136194-77-9

CAS NO: 136194-77-9
Go6976 Go-6976
CBNumber: CB1396876
Chemical Name: GO 6976
Molecular Formula: C24H18N4O
Formula Weight: 378.43
CAS No.: 136194-77-9
Description Review
Description

Go6976, also known as Go-6976, is a selective inhibitor of protein kinase C (PKC), which plays a critical role in cellular signaling and regulation. It is primarily used for research purposes to study the function and activity of PKC in various biological processes.

Chemical name: 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Molecular formula: C26H22N4O3

Formula weight: 430.47 g/mol

CAS No: 136194-77-9

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Synonyms: N-[9-[(1S,2S)-1-Ethoxycarbonyl-2-methylpropyl]-6-fluoro-2,3-dihydro-1H-indol-5-yl]acetamide; 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Health benefits of this product:

Go6976 has no established health benefits outside of its use in laboratory research. It is a tool compound that is used to study the function and activity of PKC in various cellular processes, including cell proliferation, differentiation, and apoptosis.

Potential effects:

In addition to its use in research, Go6976 may have potential therapeutic applications in certain diseases that involve abnormal PKC activity, such as cancer, heart disease, and inflammation. However, further research is needed to determine its safety and efficacy in these contexts.

Product mechanism:

Go6976 is a selective inhibitor of PKC, which is a family of serine/threonine kinases that play a critical role in signal transduction and cellular regulation. PKC is involved in a wide range of cellular processes, including cell proliferation, differentiation, apoptosis, and inflammation. By inhibiting the activity of PKC, Go6976 can modulate these processes and provide insights into their underlying mechanisms.

Safety:

As a research tool, Go6976 is not intended for human consumption and there is limited information available on its safety profile. However, it is a potent inhibitor of PKC and may have potential toxicity at high doses or with prolonged exposure.

Side effects:

There are no established side effects of Go6976 outside of its use in laboratory research. However, it may have potential toxic effects on cells or tissues that rely on PKC signaling for normal function, such as the cardiovascular system or immune system.

Dosing information:

Go6976 is typically used in laboratory research at concentrations ranging from nanomolar to micromolar depending on the experimental design and cell/tissue type being studied. There is no established dosing information for human use.

Conclusion:

Go6976 is a selective inhibitor of PKC that is primarily used as a research tool to study the function and activity of PKC in various cellular processes. While it may have potential therapeutic applications in certain diseases that involve abnormal PKC activity, further research is needed to determine its safety and efficacy in these contexts. As with all research tools, it should be used in accordance with good laboratory practices and caution should be exercised when interpreting results obtained with Go6976

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