Irbesartan (CAS: 138402-11-6) is a medication used to treat hypertension, or high blood pressure. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs), which work by blocking the action of a hormone called angiotensin II, thereby relaxing blood vessels and decreasing blood pressure.
Chemical name: 2-butyl-3-{[2'-(1h-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
Molecular formula: C25H28N6O
Formula weight: 428.54 g/mol
CAS No: 138402-11-6
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Health benefits of this product: Irbesartan has demonstrated potential health benefits in reducing blood pressure and subsequently lowering the risk of cardiovascular diseases such as stroke, heart attack, or kidney disease. Its primary mode of action is through antagonizing the effect of angiotensin II on blood vessels.
Potential effects: Irbesartan has demonstrated efficacy in several clinical studies in reducing blood pressure levels and preventing the progression of cardiovascular disease. It also has potential benefits for improving kidney function and reducing proteinuria (the presence of excess protein in urine), particularly in patients with diabetes. Irbesartan works by blocking the action of angiotensin II, which can lead to improved blood flow and reduced stress on the heart and kidneys.
Product mechanism: Irbesartan works by selectively blocking the action of angiotensin II on specific receptors in blood vessels. By doing so, it relaxes blood vessels and improves blood flow, ultimately leading to a decrease in blood pressure levels. Additionally, Irbesartan may reduce proteinuria and protect kidney function by reducing the overactivity of the renin-angiotensin system (RAS).
Safety: Irbesartan has been evaluated in several clinical trials involving thousands of patients and has been generally well-tolerated. Common side effects may include dizziness, headache, fatigue, nausea, or diarrhea. Patients with liver or kidney disease should exercise caution when taking Irbesartan, as it may affect these conditions. Pregnant women should avoid using Irbesartan, as it may harm the fetus.
Side effects: Less common but more severe side effects of Irbesartan may include low blood pressure, allergic reactions, or kidney dysfunction, which may require prompt medical intervention. Patients should be monitored closely for these adverse events and receive appropriate medical intervention if necessary.
Dosing information: The optimal dose and dosing regimen of Irbesartan may vary depending on the patient's condition and treatment goals. In clinical studies, doses ranging from 75 to 300 mg per day have been evaluated for hypertension and cardiovascular disease. Patients should follow their doctor's instructions regarding dosing, administration, and monitoring.
Conclusion: Irbesartan (CAS: 138402-11-6) is an angiotensin II receptor blocker (ARB) used to treat hypertension and prevent cardiovascular diseases such as stroke, heart attack, or kidney disease. It works by blocking the action of angiotensin II, relaxing blood vessels, and improving blood flow. Although generally well-tolerated in clinical trials, it may cause some side effects that should be monitored closely. More research is needed to determine its full potential and efficacy in different patient populations and cardiovascular disease types. Irbesartan offers a promising avenue for the treatment of hypertension and related conditions by antagonizing the effect of angiotensin II on blood vessels.
