Manidipine hydrochloride is a calcium channel blocker (CCB) medication used to treat hypertension (high blood pressure). The chemical name of Manidipine hydrochloride is 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-carbethoxy-5-methoxypropyl ester hydrochloride. The molecular formula of Manidipine hydrochloride is C35H40ClN3O8, and its molecular weight is 674.17 g/mol. The CAS number of Manidipine hydrochloride is 89226-75-5.
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Synonyms: Manidipine HCl, CV-4093, 1, 4-Dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-3, 5-pyridinedicarboxylic acid 3-carbethoxy-5-methoxypropyl ester hydrochloride.
Health benefits of this product: Manidipine hydrochloride has been shown to be effective in reducing high blood pressure and improving hypertension-related symptoms. It may also have beneficial effects on the function of the heart and blood vessels.
Potential effects: Manidipine hydrochloride works by blocking the entry of calcium ions into vascular smooth muscle cells, which can help relax the muscles and widen blood vessels. This leads to improved blood flow and reduced blood pressure. Additionally, it may have cardioprotective effects, such as reducing the risk of stroke and other cardiovascular events.
Product mechanism: Manidipine hydrochloride belongs to the class of drugs known as calcium channel blockers. It works by blocking the entry of calcium ions into vascular smooth muscle cells, leading to relaxation of the muscles and dilation of blood vessels. This results in decreased resistance to blood flow and lower blood pressure.
Safety: Manidipine hydrochloride has been shown to be safe and well-tolerated in clinical trials. However, as with any medication, there is a potential for side effects, and it should be used with caution in patients with certain medical conditions or taking certain medications.
Side effects: Common side effects of Manidipine hydrochloride include headache, dizziness, flushing, and peripheral edema. Rare but serious side effects include an allergic reaction, liver damage, and low blood pressure.
Dosing information: The recommended dosage of Manidipine hydrochloride varies depending on the patient's age, medical history, and other factors. Typically, it is taken once daily at a dose of 10 mg.
Conclusion: In conclusion, Manidipine hydrochloride is a useful medication for the treatment of hypertension and related symptoms. It works by blocking the entry of calcium ions into vascular smooth muscle cells, leading to relaxation of the muscles and dilation of blood vessels. While generally well-tolerated, it should be used with caution and under the supervision of a healthcare professional. With proper use and monitoring, Manidipine hydrochloride can help improve blood pressure and reduce the risk of cardiovascular events
