Matrine is a natural product that belongs to the family of quinolizidine alkaloids. It is found in certain plants such as Sophora flavescens and Sophora alopecuroides, which have been used in traditional Chinese medicine for centuries. Matrine has gained much attention over recent years due to its potential health benefits, including anti-inflammatory, anti-tumor, and liver protective effects.
The chemical name of Matrine is (1R)-1,2-didehydro-1-methyl-2-(1-methylpropyl)pyrrolizinium.
The molecular formula of Matrine is C15H24N2.
The formula weight of Matrine is 232.37 g/mol.
The CAS number of Matrine is 519-02-8.
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Synonyms of Matrine include Sophocarpine-14-carboxylic acid, and (1R)-1,2-didehydro-1-methyl-2-(1-methylpropyl)pyrrolizinium.
Health benefits of this product:
Matrine has been reported to have various health benefits, including its ability to reduce inflammation, prevent or treat cancer, and protect the liver.
Anti-inflammatory: Matrine possesses potent anti-inflammatory effects, which can help alleviate inflammation-related conditions such as arthritis and asthma.
Anti-tumor: Matrine possesses potent anti-tumor properties, which can help prevent or treat cancers such as lung, breast, and prostate.
Liver protection: Matrine has been shown to have hepatoprotective effects by reducing liver enzyme levels, improving liver function, and protecting against liver damage.
In addition to its health benefits, Matrine may have other potential effects. For example, it has been reported to possess immune-stimulating properties, making it beneficial for individuals with weakened immune systems. It may also have cardiovascular protective effects, such as lowering blood pressure and preventing atherosclerosis. Additionally, it may have neuroprotective effects, making it beneficial for individuals with neurological disorders such as Alzheimer's disease.
The exact mechanism of action of Matrine is not fully understood, but it is believed to exert its effects through multiple pathways. For example, it may inhibit certain signaling pathways involved in tumor growth and metastasis or activate enzymes involved in detoxification and antioxidant defense.
Matrine is generally considered safe when consumed in moderate amounts. However, high doses may cause gastrointestinal upset, such as nausea and diarrhea.
Matrine is generally well-tolerated, but some individuals may experience side effects, especially at high doses. These can include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Allergic reactions are also possible, although rare.
There is no standard dosing recommendation for Matrine as its optimal dose may vary depending on the individual, the condition being treated, and the form in which it is consumed. However, most studies have used doses ranging from 50 to 200 mg per day.
Matrine is a natural product with numerous potential health benefits, including its ability to reduce inflammation, prevent or treat cancer, and protect the liver. Its safety profile is generally good when consumed in moderation, and it may offer additional benefits such as immune-stimulating and cardiovascular protective effects. However, more research is needed to fully understand its mechanisms of action and optimal dosing strategies. Overall, Matrine is a promising compound that deserves further investigation for its potential therapeutic applications in traditional Chinese medicine