N-desethyl Isotonitazene

CAS NO: 06045
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Formal Name :N-ethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)ethan-1-amine, monohydrochloride
Purity : ≥98%
DMF: 30 mg/ml
InChi Key : YGIGEJHYUUWLMA-UHFFFAOYSA-N
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Description
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N-desethyl Isotonitazene is a synthetic opioid drug that belongs to the class of benzimidazole derivatives. It has been identified as an emerging drug of abuse and has been associated with a growing number of opioid-related deaths in recent years. The chemical name for N-desethyl Isotonitazene is 5-(2-iodo-4,5-dihydro-1H-benzo[d]imidazol-1-yl)-1,3-dihydro-2H-indol-2-one, and it has a molecular formula of C18H17IN2O with a formula weight of 426.25 g/mol. It is identified by CAS No. 14188-81-9.

Chemical Name:

The chemical name for N-desethyl Isotonitazene is 5-(2-iodo-4,5-dihydro-1H-benzo[d]imidazol-1-yl)-1,3-dihydro-2H-indol-2-one.

Molecular Formula:

The molecular formula for N-desethyl Isotonitazene is C18H17IN2O.

Formula Weight:

The formula weight for N-desethyl Isotonitazene is 426.25 g/mol.

CAS Number:

The CAS number for N-desethyl Isotonitazene is 14188-81-9.

Top Ten Keywords from Google and Synonyms:

  1. Synthetic opioids
  2. Benzimidazole derivatives
  3. Emerging drug of abuse
  4. Opioid epidemic
  5. Designer drugs
  6. Novel psychoactive substances
  7. CAS 14188-81-9
  8. N-deisopropyl Isotonitazene
  9. NDIsotonitazene
  10. Legal highs

Health Benefits of N-desethyl Isotonitazene:

N-desethyl Isotonitazene does not have any health benefits. It is primarily used as a recreational drug and has no therapeutic value.

Potential Effects of N-desethyl Isotonitazene:

N-desethyl Isotonitazene is a potent opioid drug that produces effects similar to those of other opioids such as morphine and fentanyl. It is known to produce feelings of euphoria, pain relief, and sedation. However, it is also associated with significant risks and potential adverse effects, including respiratory depression, overdose, and addiction.

Product Mechanism:

N-desethyl Isotonitazene works by binding to and activating specific receptors in the brain and spinal cord called mu-opioid receptors. This activation leads to the release of neurotransmitters such as dopamine and serotonin, which produce the characteristic euphoric and analgesic effects of opioids.

Safety:

N-desethyl Isotonitazene is considered extremely dangerous and potentially lethal. It is associated with a high risk of overdose and death due to its potency and the difficulty in accurately dosing the drug. Additionally, it is often found mixed with other drugs, making it difficult to determine the actual composition and strength of the substance.

Side Effects:

The side effects of N-desethyl Isotonitazene include respiratory depression, sedation, confusion, dizziness, nausea, vomiting, and constipation. Prolonged use can lead to tolerance, dependence, and addiction. Overdose can result in respiratory arrest, coma, and death.

Dosing Information:

There is no safe or recommended dosing information for N-desethyl Isotonitazene. Due to its potency and unpredictable nature, even small amounts of the drug can be lethal.

Conclusion:

N-desethyl Isotonitazene is a synthetic opioid drug that poses significant risks and dangers to users. It is associated with a high risk of overdose and death, and its use has been linked to a growing number of opioid-related deaths in recent years. While it produces effects similar to those of other opioids, it lacks any therapeutic value and is primarily used as a recreational drug. As an emerging drug of abuse, N-desethyl Isotonitazene highlights the ongoing challenges associated with the opioid epidemic and underscores the need for continued efforts to prevent and treat opioid abuse and addiction.




N-Desethyl Isotonitazene is a new opioid of the 2-benzyl benzimidazole subclass that differs structurally from fentanyl. New opioids have been shown to provide psychoactive effects comparable to heroin, fentanyl, and other opioids. According to the literature, novel opioids have also produced adverse outcomes, including death. N-Desethyl Isotonitazene is a recognized metabolite of isotonitazene; nevertheless, it is currently being synthesized and disseminated as a parent drug on its own, as evidenced by sales on online gray market sites and the identification of this substance in drug materials lacking isotonitazene. Studies indicate that this class of analogues may have potencies comparable to or greater than fentanyl. N-desethyl isotonitazene has the same efficacy as etonitazene in vitro.

InChI=1S/C21H26N4O3.ClH/c1-4-22-11-12-24-20-10-7-17(25(26)27)14-19(20)23-21(24)13-16-5-8-18(9-6-16)28-15(2)3;/h5-10,14-15,22H,4,11-13H2,1-3H3;1H
DMSO: 30 mg/ml
Formula Weight : 418.9
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: 30 mg/ml
Molecular Formula :C21H26N4O3 • HCl 
PBS (pH 7.2): 5 mg/ml
λmax
240, 301 nm
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