Nateglinide is an oral medication used in the treatment of type 2 diabetes. It is a chemical compound with the chemical name (S)-N-[3-phenyl-2-(1-piperidinyl)propyl]propanamide and has the molecular formula C19H27NO3. Its formula weight is 317.43 g/mol, and its CAS number is 105816-04-4.
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Synonyms for Nateglinide include A-4166, D-1540, and Starlix.
Health benefits of Nateglinide:
Nateglinide is primarily used in the treatment of type 2 diabetes to manage blood glucose levels. It stimulates insulin secretion from pancreatic beta cells in response to food intake, thus lowering postprandial hyperglycemia. As a result, it can help improve glycemic control in patients with type 2 diabetes.
Potential effects of Nateglinide:
The primary effect of Nateglinide is stimulation of insulin secretion from pancreatic beta cells. This leads to lower blood glucose levels after meals, particularly in patients with type 2 diabetes who exhibit impaired insulin secretion. Additionally, Nateglinide has been shown to have a rapid onset of action, allowing for more precise control of postprandial hyperglycemia.
The mechanism of action of Nateglinide involves stimulation of insulin secretion from pancreatic beta cells via inhibition of ATP-sensitive potassium channels. This results in an increase in intracellular calcium concentration, which leads to exocytosis of insulin-containing granules.
Nateglinide has been tested in preclinical studies and clinical trials, and its safety profile has been well-established. However, like any other drug, there may be some side effects associated with its use. Therefore, it is important to consult a physician before taking this drug.
Some of the common side effects associated with the use of Nateglinide include headache, dizziness, nausea, and hypoglycemia. In rare cases, more serious side effects such as liver toxicity have been reported.
The dosing of Nateglinide varies depending on the individual patient and their response to treatment. Therefore, it is important to follow the dosage instructions provided by a healthcare professional. Nateglinide is typically taken orally before meals.
Nateglinide is a useful medication for the management of blood glucose levels in patients with type 2 diabetes. As an insulin secretagogue, it can stimulate insulin secretion from pancreatic beta cells and lower postprandial hyperglycemia. While its safety profile has been established, it is important to consult with a healthcare professional before taking this drug