NVP-BGJ398 (also known as BGJ398) is a chemical compound that is used in scientific research as an inhibitor of fibroblast growth factor receptors (FGFRs). This inhibition has potential applications in treating certain medical conditions related to abnormal cell growth, such as cancer.
Chemical name: The chemical name of NVP-BGJ398 is 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-(1-methylpiperidin-4-yl)pyrimidine-2-amine.
Molecular formula: The molecular formula of NVP-BGJ398 is C19H22Cl2N4O2.
Formula weight: The molecular weight of NVP-BGJ398 is 426.31 g/mol.
CAS No: The CAS number of NVP-BGJ398 is 872511-34-7.
Top ten keywords from Google and Synonyms:
Synonyms: • BGJ398 • NVP-BGJ-398 • Infigratinib • 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-(1-methylpiperidin-4-yl)pyrimidine-2-amine
Health benefits of this product: NVP-BGJ398 inhibits the activity of fibroblast growth factor receptors (FGFRs), which play a role in various cellular processes like cell proliferation, differentiation, migration, and survival. By inhibiting FGFRs, NVP-BGJ398 can potentially affect these processes, leading to changes in cell behavior, including cell cycle arrest or apoptosis. This inhibition has potential applications in treating certain medical conditions related to abnormal cell growth, such as cancer.
Potential effects: NVP-BGJ398 inhibits the activity of fibroblast growth factor receptors (FGFRs), which play a role in various cellular processes like cell proliferation, differentiation, migration, and survival. By inhibiting FGFRs, NVP-BGJ398 can potentially affect these processes, leading to changes in cell behavior, including cell cycle arrest or apoptosis. This inhibition has potential applications in treating certain medical conditions related to abnormal cell growth, such as cancer.
Product mechanism: NVP-BGJ398 inhibits the activity of fibroblast growth factor receptors (FGFRs) by binding to the active site of the enzyme. FGFRs are involved in various cellular processes, including cell proliferation, differentiation, migration, and survival. By inhibiting FGFRs, NVP-BGJ398 can block these processes and potentially reduce abnormal cell growth.
Safety: NVP-BGJ398 is mainly used in scientific research and has not been approved for human use. Its safety in humans is not well established, and there may be potential side effects associated with its use. Individuals should seek advice from a healthcare professional before using NVP-BGJ398.
Side effects: The potential side effects of NVP-BGJ398 are not well-established as it is primarily used in scientific research. However, there may be potential risks associated with its use, including toxicity and effects on normal cell growth.
Dosing information: NVP-BGJ398 is mainly used in scientific research and dosing information is determined based on the specific experiment being performed. Individuals should consult with a qualified scientist or healthcare professional for guidance on appropriate dosing.
Conclusion: NVP-BGJ398 is a chemical compound that is commonly used in scientific research as an inhibitor of fibroblast growth factor receptors (FGFRs). The inhibition of FGFRs has potential applications in treating certain medical conditions related to abnormal cell growth, such as cancer. Although mainly used in scientific research, potential side effects and safety concerns should be taken into consideration if considering its use. Further studies are needed to determine the safety and efficacy of NVP-BGJ398 for human use.
