Omacetaxine, also known as Homoharringtonine, is a type of chemotherapy medication used to treat chronic myeloid leukemia. It belongs to the class of drugs called protein synthesis inhibitors that prevent cancer cells from growing and dividing. Omacetaxine Homoharringtonine CAS: 26833-87-4 is the chemical compound that has been widely studied for its effectiveness in treating this type of leukemia.
The chemical name for Omacetaxine Homoharringtonine is (1S,3R,4R,5R,8R,9S,10R,11S,12R,13R)-3-((2S,3R,4S,6R)-4-amino-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-9,13-dimethyl-5-(1-methylpropyl)oxacyclododeca[3,2-d]pyridin-2,4,6,12(1H,3H,5H,7H,8H,9H,11H)-heptone.
The molecular formula of Omacetaxine Homoharringtonine is C29H39N5O8.
The formula weight of Omacetaxine Homoharringtonine is 569.65 g/mol.
The CAS number for Omacetaxine Homoharringtonine is 26833-87-4.
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Other synonyms for Omacetaxine Homoharringtonine include Ceflatonin, Homoharringtonine Sulfate, NSC-107010, and HHT.
Omacetaxine Homoharringtonine has been shown to be effective in the treatment of chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow. It works by slowing down or stopping the growth and division of cancer cells. Studies have shown that Omacetaxine Homoharringtonine can help patients with chronic myeloid leukemia who have become resistant to other treatments.
The potential effects of Omacetaxine Homoharringtonine include decreased production of white blood cells, red blood cells, and platelets. This can lead to an increased risk of infections, bleeding, and anemia. Other potential effects include fatigue, nausea, vomiting, diarrhea, fever, muscle pain, and dizziness.
Omacetaxine Homoharringtonine works by inhibiting protein synthesis in cancer cells. Specifically, it binds to the ribosome, which is responsible for assembling proteins, and prevents it from working properly. This slows down or stops the growth and division of cancer cells.
Omacetaxine Homoharringtonine should only be used under the supervision of a qualified healthcare provider. It can cause serious side effects, including decreased production of blood cells, liver damage, and kidney damage. Patients who are allergic to Omacetaxine Homoharringtonine or any of its ingredients should not use this medication. It is important to tell your healthcare provider about all medications you are taking before starting treatment with Omacetaxine Homoharringtonine.
Common side effects of Omacetaxine Homoharringtonine include fatigue, nausea, vomiting, diarrhea, fever, muscle pain, and dizziness. Less common side effects include respiratory infections, anemia, and decreased appetite. Serious side effects may include decreased production of blood cells, liver damage, and kidney damage.
The dose of Omacetaxine Homoharringtonine will depend on the patient's age, weight, and overall health. The medication is usually given as an injection into the muscle or vein. Treatment may continue for several weeks or months.
Omacetaxine Homoharringtonine is a chemotherapy medication used to treat chronic myeloid leukemia. It works by inhibiting protein synthesis in cancer cells, slowing down or stopping their growth and division. While it can be effective in treating this type of leukemia, it can also cause serious side effects and should only be used under the supervision of a qualified healthcare provider