Pirfenidone CAS: 53179-13-8 is a medication that has been approved for the treatment of idiopathic pulmonary fibrosis (IPF), a chronic lung disease that causes scarring and inflammation in the lungs. It is also being studied for its potential to treat other conditions such as liver fibrosis and kidney disease.
Chemical Name:
Pirfenidone is also known as 5-methyl-1-phenyl-2-(1H)-pyridone.
Molecular Formula:
The molecular formula of Pirfenidone is C12H11NO.
Formula Weight:
The formula weight of Pirfenidone is 185.22 g/mol.
CAS No:
The CAS number of Pirfenidone is 53179-13-8.
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Health Benefits of Pirfenidone:
Pirfenidone is primarily used to treat idiopathic pulmonary fibrosis (IPF). However, it has also shown potential to treat other conditions such as liver fibrosis and kidney disease. Some of the potential benefits of Pirfenidone include:
Reduced Lung Scarring: Pirfenidone can reduce the scarring and inflammation in the lungs caused by IPF.
Improved Lung Function: Pirfenidone can improve lung function and quality of life in individuals with IPF.
Reduced Liver and Kidney Fibrosis: Pirfenidone may reduce the fibrosis or scarring in the liver and kidneys caused by certain diseases.
Potential Effects:
Pirfenidone can produce a range of effects depending on the condition being treated and individual response. Some of the potential effects of Pirfenidone include:
Reduced Lung Scarring: Pirfenidone can reduce the scarring and inflammation in the lungs caused by IPF.
Improved Lung Function: Pirfenidone can improve lung function and quality of life in individuals with IPF.
Reduced Liver and Kidney Fibrosis: Pirfenidone may reduce the fibrosis or scarring in the liver and kidneys caused by certain diseases.
Product Mechanism:
Pirfenidone works by reducing inflammation and preventing fibrosis, or the excessive production of connective tissue that can lead to scarring and organ dysfunction. It does this by blocking several pathways involved in fibrosis and inflammation, including TGF-beta, TNF-alpha, and IL-1 beta signaling.
Safety:
Pirfenidone is generally safe when used appropriately and under medical supervision. However, it can cause adverse effects in some individuals. Some of the potential side effects of Pirfenidone include:
Nausea: Pirfenidone may cause nausea or gastrointestinal disturbances in some individuals.
Skin Rash: Pirfenidone may cause a skin rash in some individuals.
Photosensitivity: Pirfenidone may increase sensitivity to sunlight.
Dosing Information:
The appropriate dose of Pirfenidone depends on the individual's age, weight, and health status. It is important to follow dosing instructions carefully and only use Pirfenidone under medical supervision.
Conclusion:
Pirfenidone is a medication that has been approved for the treatment of idiopathic pulmonary fibrosis (IPF) and is being studied for its potential to treat other conditions such as liver fibrosis and kidney disease. It works by reducing inflammation and preventing fibrosis, or the excessive production of connective tissue that can lead to scarring and organ dysfunction. While Pirfenidone may provide some health benefits, it should only be used under medical supervision and with caution due to its potential side effects