Plinabulin, also known as NPI-2358 or NPI2358, is a medication used in the treatment of cancer. It has gained attention in recent years due to its potential therapeutic benefits in reducing tumor growth and improving chemotherapy outcomes.
Introduce this product: Plinabulin is a small molecule that acts as a vascular disrupting agent (VDA), which means it can selectively disrupt the blood supply to tumors, leading to their regression. It also has immunomodulatory effects and can enhance the anti-tumor activity of chemotherapy.
Chemical name: The chemical name of Plinabulin is 3-[(2R)-2-[[(1S)-1-Amino-3-methylbutyl]oxy]-3-methoxyphenyl]-5-benzofuranmethanol.
Molecular formula: The molecular formula of Plinabulin is C22H29NO4.
Formula weight: The formula weight of Plinabulin is 371.48 g/mol.
CAS No: The CAS number of Plinabulin is 714272-27-2.
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Synonyms for Plinabulin include NPI-2358 and NPI2358.
Health benefits of this product: Plinabulin has the potential to provide numerous health benefits in the treatment of cancer. As a VDA, it can selectively disrupt the blood supply to tumors, leading to their regression. Additionally, Plinabulin has immunomodulatory effects and can enhance the anti-tumor activity of chemotherapy, leading to improved treatment outcomes.
Potential effects: The potential effects of Plinabulin are vast and varied. Its ability to selectively disrupt the blood supply to tumors makes it a promising candidate for the treatment of various types of cancer. Additionally, Plinabulin has shown promise in combination with chemotherapy and other immunotherapies in improving treatment outcomes.
Product mechanism: Plinabulin works by selectively disrupting the blood supply to tumors, leading to their regression. It does so by inhibiting microtubule polymerization, which leads to the destabilization of tumor vasculature. Additionally, Plinabulin has immunomodulatory effects, which can enhance the anti-tumor activity of chemotherapy.
Safety: Plinabulin has undergone extensive clinical trials and has been found to be safe and effective in the treatment of cancer. However, as with any medication, there is always some risk of side effects, and it is essential to consult a healthcare professional before starting any new medication or treatment regimen.
Side effects: Some potential side effects of Plinabulin may include fatigue, headaches, and gastrointestinal distress. Additionally, there is a potential risk of cardiac toxicity, so regular monitoring of cardiovascular function is necessary during treatment.
Dosing information: The dosing of Plinabulin will vary depending on the individual patient's medical condition, age, weight, and other factors. It is essential to follow the recommended dosing instructions provided by a healthcare professional, as taking too much or too little can affect its effectiveness and safety.
Conclusion: In conclusion, Plinabulin shows significant potential in treating various types of cancer. As a VDA, it provides greater specificity and fewer side effects than non-selective treatments. However, more research is needed to confirm its efficacy and safety in treating other medical conditions. It is essential to consult a healthcare professional before starting any new medication or treatment regimen.