RG108 RG-108 N-Phthalyl-L-tryptophan CAS: 48208-26-0

RG108, also known as N-Phthalyl-L-tryptophan, is a small molecule inhibitor of DNA methyltransferase (DNMT) that has been studied for its potential use in cancer therapy and epigenetic research. This product is able to target specific DNMT enzymes and reduce their activity, which can lead to the re-expression of silenced genes and potentially inhibit tumor growth.

Chemical name: (2S)-2-(1H-Indol-3-yl)-N-(phtalimido)propionamide Molecular formula: C20H16N2O4 Formula weight: 344.35 g/mol CAS No: 48208-26-0

Top ten keywords from Google and synonyms:

1. RG108: The chemical name for N-Phthalyl-L-tryptophan.
2. DNMT: An enzyme responsible for adding methyl groups to DNA.
3. Epigenetics: The study of changes in gene expression without changing the underlying DNA sequence.
4. Cancer therapy: Treatment used to destroy or slow the growth of cancer cells.
5. Gene expression: The process by which information from a gene is used to create a functional protein.
6. Tumor growth: The abnormal proliferation of cells that results in the formation of a mass or lump.
7. Methyltransferase: An enzyme responsible for transferring methyl groups between molecules.
8. Small molecule inhibitor: A compound that can bind to and inhibit the function of a specific enzyme or protein.
9. Epigenetic research: The study of how environmental factors can affect gene expression through changes in DNA methylation or histone modification.
10. Histone modification: Chemical modifications to histone proteins that can alter gene expression.

Health benefits of this product: RG108 has shown promise in cancer therapy due to its ability to re-express silenced genes, which may help to inhibit tumor growth. It may also have applications in epigenetic research to better understand how environmental factors can affect gene expression.

Potential effects: RG108 can cause changes in gene expression by inhibiting the activity of DNMT enzymes. This can potentially lead to the re-expression of silenced genes and inhibit tumor growth.

Product mechanism: RG108 works by inhibiting the activity of DNMT enzymes, which are responsible for adding methyl groups to DNA. By reducing the activity of these enzymes, RG108 can lead to hypomethylation of DNA and the re-expression of silenced genes.

Safety: RG108 should be handled with caution, as it may be toxic if ingested or inhaled. It should only be used under the supervision of a qualified professional who is experienced in handling hazardous chemicals.

Side effects: RG108 may cause changes in gene expression, which could potentially result in unintended consequences or side effects. Further research is needed to fully understand the safety profile of this product.

Dosing information: The optimal dosage of RG108 will depend on the specific application and desired outcome. Further research is needed to determine the most effective dosages in different contexts.

In conclusion, RG108 is a small molecule inhibitor of DNMT enzymes that has shown promise in cancer therapy and epigenetic research. Its ability to target specific DNMT enzymes and reduce their activity may lead to the re-expression of silenced genes and potentially inhibit tumor growth. However, further research is needed to fully understand the safety and efficacy of this product in different contexts