Rosuvastatin Calcium Salt is an oral medication used to treat high cholesterol levels and prevent heart disease. It belongs to a class of drugs called statins, which work by inhibiting the enzyme HMG-CoA reductase, responsible for producing cholesterol in the body. In this article, we will explore the chemistry, health benefits, potential effects, product mechanism, safety, side effects, and dosing information associated with Rosuvastatin Calcium Salt.
Chemical name:
The chemical name of Rosuvastatin Calcium Salt is (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)phenyl]-3,5-dihydroxy-6-heptenoic acid calcium salt.
Molecular formula:
The molecular formula of Rosuvastatin Calcium Salt is C44H54CaF2N6O12S2.
Formula weight:
The molecular weight of Rosuvastatin Calcium Salt is 1001.14 g/mol.
CAS No:
The CAS number for Rosuvastatin Calcium Salt is 147098-20-2.
Top ten keywords from Google and Synonyms:
Synonyms:
Rosuvastatin Calcium Salt is also known by its generic name, Crestor, and by several other trade names, including Rosuvas, Rosulip, Rozavel, R2, and Rosufit.
Health Benefits:
Rosuvastatin Calcium Salt is primarily used to treat high cholesterol levels and prevent cardiovascular disease. By inhibiting the enzyme HMG-CoA reductase, the drug can lower LDL or "bad" cholesterol levels and increase HDL or "good" cholesterol levels, ultimately reducing the risk of heart attack and stroke.
Potential Effects:
In addition to its lipid-lowering effects, Rosuvastatin Calcium Salt may have other potential therapeutic applications. According to some studies, the drug may be effective in treating inflammatory conditions like rheumatoid arthritis and multiple sclerosis. It may also have neuroprotective properties and could potentially be used to treat neurological conditions like Alzheimer's disease.
Product Mechanism:
Rosuvastatin Calcium Salt works by inhibiting the enzyme HMG-CoA reductase, responsible for producing cholesterol in the body. The drug binds to the active site of the enzyme, preventing it from converting HMG-CoA into mevalonic acid, a precursor to cholesterol. This action reduces the production of cholesterol in the liver, ultimately lowering LDL or "bad" cholesterol levels and increasing HDL or "good" cholesterol levels.
Safety:
Like all drugs, Rosuvastatin Calcium Salt can cause side effects. However, most side effects are mild to moderate and can be managed with medication or other treatments. Common side effects include headache, nausea, stomach pain, muscle pain, and weakness. More serious side effects, such as liver damage and rhabdomyolysis, are rare but can occur.
Side Effects:
The most common side effects of Rosuvastatin Calcium Salt include headache, nausea, stomach pain, muscle pain, and weakness. Some patients may also experience more serious side effects, such as liver damage and rhabdomyolysis, a condition in which muscle tissue breaks down rapidly and releases toxic substances into the bloodstream. If you experience any severe or persistent side effects, you should contact your doctor immediately.
Dosing Information:
Rosuvastatin Calcium Salt is usually taken once daily, with or without food. The dose will vary based on the patient's age, weight, overall health, and other factors. The typical starting dose is 10 mg per day, with a maximum dose of 40 mg per day. The drug can take up to four weeks to reach its full effect, and regular monitoring of cholesterol levels is recommended during treatment.
Conclusion:
Rosuvastatin Calcium Salt is a widely used medication for the treatment of high cholesterol levels and prevention of cardiovascular disease. By inhibiting the enzyme HMG-CoA reductase, the drug can lower LDL or "bad" cholesterol levels and increase HDL or "good" cholesterol levels, ultimately reducing the risk of heart attack and stroke. While Rosuvastatin Calcium Salt can cause.side effects, they are generally mild to moderate and can be managed with medication or other treatments. Overall, Rosuvastatin Calcium Salt is a valuable tool in the fight against high cholesterol and heart disease.
