Strontium Ranelate is a medication used to treat osteoporosis in postmenopausal women and men at high risk of fracture. It contains strontium, a metallic element that has been shown to increase bone density and reduce the risk of fractures. In this article, we will delve into the chemical and physical properties of Strontium Ranelate, its potential health benefits, side effects, dosing information, mechanism of action, and safety.
Chemical Name, Molecular Formula, Formula Weight, CAS No The chemical name for Strontium Ranelate is strontium (2+) 2-(1-hydroxy-2-oxo-2-(4-(3-oxo-3-(triethylammonio)propyl)-1,3-dioxolan-2-yl)ethylideneamino)acetate. Its molecular formula is C12H20N2O10SSr, and its formula weight is 513.49 g/mol. The CAS number for Strontium Ranelate is 135459-87-9.
Top Ten Keywords and Synonyms
Health Benefits of Strontium Ranelate Strontium Ranelate has been shown to increase bone density and reduce the risk of fractures in postmenopausal women and men at high risk of fracture. By increasing bone formation and decreasing bone resorption, Strontium Ranelate can help prevent bone loss and maintain bone strength.
Potential Effects of Strontium Ranelate In clinical trials, Strontium Ranelate has been found to increase bone density and reduce the risk of vertebral and non-vertebral fractures in postmenopausal women and men at high risk of fracture. The drug has also been found to be well-tolerated and safe in patients with osteoporosis.
Product Mechanism Strontium Ranelate works by stimulating the activity of osteoblasts, cells that form new bone tissue, while inhibiting the activity of osteoclasts, cells that break down old bone tissue. This leads to an increase in bone density and strength, reducing the risk of fractures.
Safety Strontium Ranelate has been associated with rare but serious side effects, including cardiovascular events such as myocardial infarction and venous thromboembolism. As a result, it is only recommended for use in patients who cannot tolerate or have not responded to other osteoporosis treatments. Patients should consult their healthcare provider before starting treatment with Strontium Ranelate.
Side Effects Common side effects of Strontium Ranelate include nausea, diarrhea, headache, and rash. More serious side effects, such as cardiovascular events, are rare but have been reported in some patients.
Dosing Information The recommended dose of Strontium Ranelate is one gram per day, taken orally as two separate doses of 0.5 grams each. The drug should be taken with food and is typically prescribed for up to five years. Patients should always follow their healthcare provider's instructions when taking any medication.
Conclusion Strontium Ranelate is a medication used to treat osteoporosis in postmenopausal women and men at high risk of fracture. By increasing bone density and strength, Strontium Ranelate can help prevent bone loss and reduce the risk of fractures. However, the drug has been associated with rare but serious side effects, such as cardiovascular events, and is only recommended for use in patients who cannot tolerate or have not responded to other osteoporosis treatments. With careful monitoring and appropriate use, Strontium Ranelate could be an important treatment option for patients with osteoporosis
