Tetrandrine is a natural compound that can be found in various plant sources, including the root of the Chinese herb Stephania tetrandra. Its chemical name is (6aR,10aR)-6a,7,10,10a-tetrahydro-1-((5R,8S)-5,8-dimethyl-2-propenyl)-7-methoxy-2,3,6,6a,9,10-hexahydrobenzo(g)-quinolizine-2,9-diol, and its molecular formula is C38H42N2O6. The formula weight of Tetrandrine is 622.75 g/mol, and its CAS number is 518-34-3.
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Synonyms:
Some common synonyms for Tetrandrine include radix stephania tetrandrae extract, fang ji, and hanfangji.
Health Benefits of Tetrandrine:
Tetrandrine has been studied for its potential health benefits, many of which are attributed to its anti-inflammatory and antioxidant properties. Some of the key health benefits associated with Tetrandrine include:
Anti-inflammatory effects: Tetrandrine has been shown to possess significant anti-inflammatory properties, which may help reduce inflammation and swelling throughout the body. This may be particularly beneficial for individuals with inflammatory conditions such as arthritis, asthma, and inflammatory bowel disease.
Antioxidant activity: Tetrandrine exhibits potent antioxidant activity, which can help protect cells from oxidative stress and damage caused by free radicals. This can have a positive impact on overall health and may reduce the risk of chronic diseases such as cancer, cardiovascular disease, and neurodegenerative disorders.
Cardiovascular protection: Tetrandrine has been shown to have a beneficial effect on cardiovascular health, potentially reducing the risk of heart disease and stroke.
Potential Effects:
In addition to the health benefits listed above, Tetrandrine may also have other potential effects, including:
Analgesic activity: Some research suggests that Tetrandrine may possess analgesic properties, potentially helping to relieve pain.
Anti-cancer effects: Tetrandrine has been studied for its potential anticancer effects. Research suggests that this compound may help inhibit the growth and spread of cancer cells, potentially reducing the risk of certain types of cancer.
Product Mechanism:
The exact mechanism of action of Tetrandrine is not fully understood, but it is believed to exert its effects through a variety of pathways. One key mechanism is its ability to modulate certain signaling pathways involved in inflammation and cell growth. Tetrandrine may also scavenge free radicals and reduce oxidative stress, which can help protect cells and tissues from damage.
Safety:
Tetrandrine appears to be relatively safe when consumed in moderate amounts, although more research is needed to fully understand its safety profile. Some potential side effects of Tetrandrine may include digestive upset, nausea, and headache. It may also interact with certain medications, so it is important to use Tetrandrine under the guidance of a healthcare professional.
Dosing Information:
There is no established dosing recommendation for Tetrandrine, as it has not yet been extensively studied in human clinical trials. However, most supplements contain doses ranging from 50-200mg per day.
Conclusion:
Tetrandrine is a natural compound with potential health benefits, particularly in reducing inflammation and promoting cardiovascular health. While more research is needed to fully understand its mechanisms of action and safety profile, current evidence suggests that Tetrandrine may be a promising natural compound for promoting overall health and wellness