TIC-10 isomer TIC10 CAS: 41276-02-2

CAS NO: 41276-02-2
TIC-10 isomer TIC10
Chemical Name: 7-benzyl-10-(2-Methylbenzyl)-2,6,7,8,9,10-hexahydroiMidazo[1,2-a]pyrido[4,3-d]pyriMidin-5(3H)-one
Molecular Formula: C24H26N4O
Formula Weight: 386.49
CAS No.: 41276-02-2
Description Review
Description

TIC-10 isomer TIC10, also known as ONC201, is a small molecule compound that has recently gained attention due to its potential therapeutic effects in cancer treatment. This product is a white crystalline powder with the chemical formula C24H28N2O2 and a molecular weight of 380.50 g/mol. Its CAS number is 41276-02-2.

Top ten keywords from Google and synonyms

  1. TIC-10 isomer TIC10
  2. ONC201
  3. Cancer therapy
  4. Apoptosis inducer
  5. Glioblastoma multiforme (GBM)
  6. Antitumor agent
  7. Immunomodulatory
  8. TRAIL activator
  9. Brain cancer
  10. Mitochondrial stress inducer

Synonyms:

  • ONC201 chloride
  • 1-Cyclohexyl-4-(4-(m-tolyl)thiazol-2-yl)-1,2,3,6-tetrahydropyridine hydrochloride

Health benefits of TIC-10 isomer TIC10

TIC-10 isomer TIC10 has shown potential health benefits in various areas such as cancer therapy, particularly in glioblastoma multiforme (GBM), an aggressive form of brain cancer.

Cancer Therapy: TIC-10 isomer TIC10 has been reported to have a potent anti-tumor effect in various types of cancers such as GBM, pancreatic cancer, and colon cancer. The mechanism behind its efficacy is due to its ability to induce apoptosis, or programmed cell death, in cancer cells through activation of the TRAIL pathway. Additionally, it has been shown to induce mitochondrial stress, which triggers cancer cell death.

Immunomodulatory Effects: TIC-10 isomer TIC10 has also been reported to possess immunomodulatory effects by increasing the expression of cytokines and chemokines that recruit immune cells to the site of tumors. This enhances the body's natural immune response against cancer cells.

Potential Effects

TIC-10 isomer TIC10 has shown promise as an anti-tumor agent, particularly in glioblastoma multiforme. Its ability to induce apoptosis and mitochondrial stress provides a novel approach to halting the progression of cancer.

Product Mechanism

TIC-10 isomer TIC10 induces apoptosis in cancer cells through activation of the TRAIL pathway, a process that leads to programmed cell death. Additionally, it induces mitochondrial stress, which triggers cancer cell death. Its immunomodulatory effects enhance the body's natural immune response against cancer cells.

Safety

While TIC-10 isomer TIC10 has shown promising results in preclinical studies, further investigation into its safety in humans is required. Animal studies have not shown significant adverse effects, but more research is needed to fully understand its safety profile.

Side Effects

Currently, there is limited information regarding the side effects of TIC-10 isomer TIC10. However, as with any medication, caution should be taken, and patients should consult with their healthcare provider before use.

Dosing Information

Dosing information for TIC-10 isomer TIC10 is not yet established. Further study is necessary to determine safe and effective dosing guidelines.

Conclusion

TIC-10 isomer TIC10 has shown significant potential as a therapeutic agent in cancer therapy, particularly in glioblastoma multiforme. Its mechanism of action in inducing apoptosis and mitochondrial stress provides a novel approach to halting the progression of cancer. While more research is needed to establish safety and dosing guidelines for human use, TIC-10 isomer TIC10 shows promise as a potential treatment option. Its immunomodulatory effects suggest that it may play an important role in future cancer treatments

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