Trihydroxyethylrutin, also known as troxerutin, is a flavonoid that is commonly used as a dietary supplement due to its potential health benefits. The chemical name for this compound is 3',4',5,7-tetrahydroxyflavanone-3-[(6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside)-2-(3,4-dihydroxyphenyl)ethyl] ether. Its molecular formula is C33H42O19, and its formula weight is 742.67 g/mol. Trihydroxyethylrutin has a CAS number of 7085-55-4.
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Synonyms: Troxerutin-P, OT15980, OT-15980, 3',4',5,7-Tetrahydroxyflavanone-3-[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]-6-(3,4,5-trihydroxybenzyl)-d-glucopyranoside, Troxerutina, Troxerutinum.
Health Benefits of Trihydroxyethylrutin: Trihydroxyethylrutin (troxerutin) exhibits several potential health benefits including:
Anti-inflammatory - Trihydroxyethylrutin has been shown to reduce inflammation by inhibiting the production of inflammatory cytokines in the body.
Antioxidant properties - This flavonoid has potent antioxidant properties that help to protect cells from oxidative damage caused by free radicals.
Venous insufficiency - Trihydroxyethylrutin has been used to treat venous insufficiency, a condition where blood flow in the veins is compromised leading to swelling, pain, and varicose veins.
Edema - Trihydroxyethylrutin may help to reduce edema or swelling by improving microcirculation and enhancing lymphatic drainage.
Cardiovascular health - Research suggests that trihydroxyethylrutin may have beneficial effects on cardiovascular health by improving endothelial function, reducing blood pressure, and lowering cholesterol levels.
Potential Effects: Trihydroxyethylrutin (troxerutin) has several potential effects on the body. It may help to reduce inflammation, protect cells from oxidative damage, improve blood flow, and promote cardiovascular health.
Product Mechanism: The exact mechanism of action of trihydroxyethylrutin is not fully understood. However, it is believed to exert its effects by modulating various signaling pathways in the body. For example, it may inhibit the production of inflammatory cytokines and enhance the activity of antioxidant enzymes. Additionally, it may improve blood flow by promoting the release of nitric oxide and enhancing the expression of vascular endothelial growth factor (VEGF), which stimulates the growth of new blood vessels.
Safety: Trihydroxyethylrutin (troxerutin) is generally considered safe when taken at recommended doses. However, some people may experience mild side effects such as nausea, diarrhea, or headache.
Side Effects: Trihydroxyethylrutin (troxerutin) may cause mild side effects such as gastrointestinal upset, headache, and dizziness. These side effects are usually mild and resolve on their own after discontinuing use.
Dosing Information: The optimal dosage of trihydroxyethylrutin (troxerutin) depends on several factors such as age, weight, and medical history. As a dietary supplement, typical doses range from 300-600 mg per day.
Conclusion: Trihydroxyethylrutin (troxerutin) is a flavonoid with potent anti-inflammatory and antioxidant properties that may have several potential health benefits. It has been used to treat conditions such as venous insufficiency, edema, and cardiovascular disease. While it is generally considered safe, individuals should speak with their healthcare provider before taking any dietary supplements.
