Tubacin is a small molecule inhibitor of histone deacetylase 6 (HDAC6), an enzyme involved in the regulation of cellular processes such as protein degradation and cell motility. This product is a white powder with the chemical formula C22H24N2O3S and a molecular weight of 408.5 g/mol. Its CAS number is 537049-40-4.
Top ten keywords from Google and Synonyms
Synonyms:
Health benefits of Tubacin
Tubacin has shown potential health benefits in various areas such as cancer therapy, neuroprotection, and anti-inflammatory effects.
Cancer Therapy: Tubacin has been reported to have potent anti-tumor effects in various types of cancers such as breast cancer and leukemia. The mechanism behind its efficacy is due to its ability to inhibit HDAC6, which plays a critical role in the regulation of gene expression and cellular processes such as protein degradation and autophagy. By inhibiting this process, Tubacin can suppress the growth and proliferation of cancer cells.
Neuroprotection: Tubacin has also demonstrated neuroprotective effects in various models of neurological disorders such as Huntington's disease and Alzheimer's disease. These effects are associated with its ability to stimulate autophagy, a process by which damaged proteins and organelles are eliminated, thus preventing their accumulation and toxicity.
Anti-inflammatory Effects: Tubacin has been shown to have anti-inflammatory effects in various models of inflammation such as arthritis and asthma. These effects are associated with its ability to inhibit HDAC6, which regulates the activity of pro-inflammatory genes.
Potential Effects
Tubacin has shown promise as an anti-tumor agent in cancer therapy, as well as neuroprotective and anti-inflammatory effects. Its potential role in epigenetic regulation suggests it may also have applications in epigenetic therapy.
Product Mechanism
Tubacin inhibits HDAC6, which plays a critical role in the regulation of gene expression and cellular processes such as protein degradation and autophagy. By inhibiting this process, Tubacin can suppress the growth and proliferation of cancer cells, stimulate autophagy, and regulate the activity of pro-inflammatory genes. These effects suggest that Tubacin may have potential as an epigenetic therapy.
Safety
While Tubacin has shown promising results in preclinical studies, further investigation into its safety in humans is required. Animal studies have not shown significant adverse effects, but more research is needed to fully understand its safety profile.
Side Effects
Currently, there is limited information regarding the side effects of Tubacin. However, caution should be taken, and patients should consult with their healthcare provider before use.
Dosing Information
Dosing information for Tubacin is not yet established. Further study is necessary to determine safe and effective dosing guidelines.
Conclusion
Tubacin has shown significant potential as a therapeutic agent in various fields of medicine, particularly in cancer therapy, neuroprotection, and anti-inflammatory effects. Its ability to inhibit HDAC6 provides a novel approach to regulating gene expression and cellular processes such as protein degradation and autophagy. While more research is needed to establish safety and dosing guidelines for human use, Tubacin shows promise as a potential treatment option. Its ability to inhibit HDAC6 suggests that it may play an important role in future cancer treatments and as a neuroprotective and anti-inflammatory agent
