Fluxametamide is a new isoxazoline pesticide that works by antagonizing insect ligand-gated chloride channels.
Molecular Weight : 474.26
Formula : C20H16Cl2F3N3O3
In contrast to its substantial effects on arthropod LGCCs, fluxametamide's antagonistic activity against rat GABACls and human glycine-gated chloride channels was negligible, indicating that fluxametamide has a strong target-site selectivity for arthropods over mammals. Overall, fluxametamide is a novel LGCC antagonist pesticide with outstanding target-site safety for animals.