4-Methylbenzophenone, also known as 4-MBP, is a chemical compound widely used in the manufacturing of various consumer products. Its chemical name is 4-(4-methylphenyl)phenylmethanone, with a molecular formula of C14H12O and formula weight of 196.25 g/mol. The CAS number for 4-MBP is 134-84-9. It is an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also an essential ingredient in the production of perfumes and sunscreens.
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Health Benefits of 4-Methylbenzophenone
4-Methylbenzophenone absorbs ultraviolet (UV) light and is commonly used as a UV absorber in sunscreens and other skin-care products. It helps in the prevention of skin damage and skin cancer due to sunburn. With the growing awareness of the harmful effects of UV radiation, the use of 4-MBP in personal care products may have a positive impact on public health.
Potential Effects of 4-Methylbenzophenone
While 4-MBP has several uses and benefits, its potential effects need to be considered as well. According to research, 4-Methylbenzophenone derivatives have been shown to have estrogenic activity, which may affect the endocrine system, leading to developmental and reproductive disorders.
Product Mechanism of 4-Methylbenzophenone
4-Methylbenzophenone, as a UV absorber, is a chemical that absorbs UV energy from the sun, blocking the skin's absorption of UV radiation. This process helps to prevent DNA damage and the development of skin cancer.
Safety of 4-Methylbenzophenone
The safety of 4-Methylbenzophenone and its derivatives has been a topic of concern for many years. The European Union has classified 4-Methylbenzophenone as a Category 3 skin sensitizer, which means that it has a moderate potential for skin sensitization. The National Toxicology Program (NTP) has listed 4-Methylbenzophenone as reasonably anticipated to be a human carcinogen based on studies in experimental animals. However, studies on humans have shown no evidence to support this claim. The use of 4-MBP in personal care products is regulated, and the concentration of the compound is restricted to a maximum of 4% in cosmetics.
Side Effects of 4-Methylbenzophenone
Exposure to 4-Methylbenzophenone can cause skin irritation and allergic reactions, especially in individuals with sensitive skin. Long-term exposure may cause endocrine disruption leading to developmental and reproductive disorders. While rare, ingestion of 4-MBP may cause severe toxicity and must be treated immediately.
Dosing Information
The dosing information for 4-Methylbenzophenone depends on the type of product in which it is present. In sunscreens, it is usually present in concentrations ranging from 1-8% for effective protection against UV radiation. In industrial applications, the dosing is much higher, with concentrations reaching up to 50%.
Conclusion
4-Methylbenzophenone is a widely used chemical compound found in many consumer products, including sunscreens and other personal care products, industrial products, and pharmaceuticals. While it has several benefits, including its ability to protect against UV radiation, its potential effects on human health cannot be overlooked. It is important to note that the use of 4-Methylbenzophenone in personal care products is regulated and concentrations are limited to ensure its safe use. Individuals using products containing 4-MBP should be aware of its potential side effects, and immediate medical attention must be sought in case of poisoning
