Alogliptin is a medication used to treat type 2 diabetes. It is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, which means that it works by blocking the enzyme responsible for breaking down incretin hormones. These hormones help regulate blood sugar levels by stimulating insulin secretion and reducing glucose production in the liver.
Chemical Name
The chemical name of Alogliptin is (2S)-2-[3-[(R)-3-amino-1-piperidinyl]-1-adamantyl]-2-oxo-1-pyrrolidinecarbonitrile.
Molecular Formula
The molecular formula of Alogliptin is C18H21N5O2.
Formula Weight
The formula weight of Alogliptin is 339.39 g/mol.
CAS No
The CAS number for Alogliptin is 850649-61-5.
Top Ten Keywords from Google and Synonyms
Synonyms:
Health Benefits of this Product
Alogliptin has been shown to effectively lower blood sugar levels in patients with type 2 diabetes. By inhibiting the DPP-4 enzyme, it increases the levels of incretin hormones in the body, leading to increased insulin secretion and decreased glucose production in the liver. This results in improved glycemic control and reduced risk of complications associated with high blood sugar levels.
Potential Effects
Besides its primary function of lowering blood sugar levels, Alogliptin also has some potential additional effects that may be beneficial for individuals with type 2 diabetes. These include:
Cardiovascular benefits: Some studies have suggested that DPP-4 inhibitors like Alogliptin may have cardiovascular benefits, such as reducing the risk of heart attack and stroke.
Weight loss: DPP-4 inhibitors have been associated with modest weight loss in some patients, which may be helpful for those who are overweight or obese.
Anti-inflammatory effects: Alogliptin has been shown to have anti-inflammatory effects in some animal studies, which may be beneficial for individuals with diabetes who are at increased risk of inflammation-related complications.
Product Mechanism
Alogliptin works by inhibiting the DPP-4 enzyme, which is responsible for breaking down incretin hormones like glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). These hormones play a crucial role in regulating blood sugar levels by stimulating insulin secretion and reducing glucose production in the liver.
By inhibiting DPP-4, Alogliptin increases the levels of these hormones in the body, resulting in increased insulin secretion and decreased glucose production in the liver. This leads to improved glycemic control and reduced risk of complications associated with high blood sugar levels.
Safety
Alogliptin is generally considered safe and well-tolerated. However, like all medications, it can cause side effects in some individuals. Common side effects of Alogliptin include headache, nasopharyngitis (inflammation of the nose and throat), and upper respiratory tract infection.
Rare but serious side effects of Alogliptin include pancreatitis (inflammation of the pancreas), hypersensitivity reactions, and severe joint pain. Patients should seek medical attention immediately if they experience any of these symptoms while taking Alogliptin.
Dosing Information
The recommended starting dose of Alogliptin is 25 mg once daily, taken orally with or without food. The dose may be increased to 50 mg once daily if additional glycemic control is needed. Alogliptin should be taken at the same time each day to maintain consistent blood levels.
Conclusion
Alogliptin is an effective medication for treating type 2 diabetes. It works by inhibiting the DPP-4 enzyme, leading to increased levels of incretin hormones, which stimulate insulin secretion and reduce glucose production in the liver. Alogliptin has been shown to effectively lower blood sugar levels and may also have additional benefits, such as cardiovascular and anti-inflammatory effects.
