AZD1480, also known as AZD-1480, is a small molecule inhibitor frequently used in cancer research. It is a pyrazolo [3,4-d] pyrimidine compound that targets the JAK2 tyrosine kinase. The chemical name for AZD1480 is N-(3-Chloro-4-((3-(trifluoromethyl)phenyl) amino)pyrazolo[3,4-d]pyrimidin-1-yl) cyclopropane-1-carboxamide. Its molecular formula is C17H13ClF3N5O, and its molar mass is 413.77 g/mol. Its CAS No is 935666-88-9.
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Some synonyms of AZD1480 include N-(3-Chloro-4-((3-(trifluoromethyl)phenyl) amino)pyrazolo[3,4-d]pyrimidin-1-yl) 1-carboxycyclopropane and AZD 1480.
Health Benefits of AZD1480
AZD1480 is still in the early stages of research, and its health benefits are still being studied. However, AZD1480 has been found to be a potent inhibitor of JAK2, and as such, it may have potential in the treatment of certain types of cancer.
Potential Effects of AZD1480
AZD1480 has been found to have the potential to inhibit the growth of cancer cells by blocking the activity of the JAK2 tyrosine kinase. This action can interfere with the growth and spread of cancer cells by blocking key signal transductions. AZD1480 may be effective in the treatment of leukemia, lymphoma, multiple myeloma, and other solid tumors.
Product Mechanism of AZD1480
AZD1480 works by inhibiting the JAK2 tyrosine kinase that is involved in the JAK STAT pathway. This pathway is critical for cell survival, growth, and proliferation. Inhibiting JAK2 activity leads to cell death or inhibition, which can limit cancer cell growth and proliferation.
Safety of AZD1480
AZD1480 is a potent inhibitor and should be handled carefully. It should be stored in a cool, dark place and kept away from sources of heat and light.
Side Effects of AZD1480
The side effects of AZD1480 are still being studied, and more research is needed to determine the safety of the product in humans. Some potential side effects of the product include low blood cell counts, thromboembolism, anemia, leukopenia, fatigue, and nausea.
Dosing Information of AZD1480
The dosing information for AZD1480 varies depending on the individual and the condition being treated. It is recommended that the product be used under the supervision of a qualified health professional.
Conclusion
AZD1480 is a small molecule inhibitor that has shown promise in cancer research by blocking the activity of the JAK2 tyrosine kinase. The product has the potential to limit cancer cell growth and proliferation, and it has been found to be effective in the treatment of leukemia, lymphoma, multiple myeloma, and other solid tumors. However, further research is needed to determine the safety and efficacy of AZD1480 in humans. As with any new product or treatment, it is recommended that individuals consult with a qualified health professional before use.
