DESMETHYL LOPERAMIDE is a synthetic opioid drug used to treat diarrhea. It is a metabolite of loperamide, and it has been shown to have stronger binding affinity for the mu-opioid receptor than its parent compound.
Chemical name: (2R)-2-[(3-methoxy-4-methylphenyl)amino]-N,N-diethyl-2-propanamine
Molecular formula: C18H28N2O
Formula weight: 288.44 g/mol
CAS No: 66164-07-6
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Health benefits of this product: DESMETHYL LOPERAMIDE is primarily used to treat acute and chronic diarrhea in adults. It works by decreasing the motility of the intestines, thereby reducing the frequency and urgency of bowel movements. It may also be used to manage symptoms associated with irritable bowel syndrome (IBS).
Potential effects: DESMETHYL LOPERAMIDE is a potent opioid receptor agonist, which means it has potential for abuse and addiction. In high doses, it can cause respiratory depression and even death. It should not be taken with alcohol or other sedatives, as this can increase the risk of overdose.
Product mechanism: DESMETHYL LOPERAMIDE acts by binding to the mu-opioid receptor in the gastrointestinal tract, which reduces the secretion of fluid and electrolytes into the intestinal lumen. This results in decreased stool volume and frequency.
Safety: DESMETHYL LOPERAMIDE should not be used in individuals with severe hepatic impairment, as it can increase the risk of toxicity. It should also be used with caution in individuals with impaired renal function, as accumulation of the drug and its metabolites can occur. It may also interact with other medications, so it should be used under the supervision of a healthcare provider.
Side effects: Common side effects of DESMETHYL LOPERAMIDE include constipation, nausea, vomiting, abdominal pain, and dry mouth. Less common side effects include dizziness, headache, and skin rash. In rare cases, it can cause respiratory depression, especially when taken in high doses.
Dosing information: DESMETHYL LOPERAMIDE is available in tablet form, and the recommended dose for adults is 2 mg every 4-6 hours as needed. The maximum daily dose should not exceed 8 mg per day. It should not be used for more than 2 days, unless directed by a healthcare provider.
Conclusion: DESMETHYL LOPERAMIDE is a potent antidiarrheal agent that works by decreasing the motility of the intestines. It has the potential for abuse and addiction, and can cause respiratory depression in high doses. It should only be used under the supervision of a healthcare provider, and for short-term treatment of diarrhea. If you experience any side effects or have any concerns about using this medication, talk to your doctor.
