Docosyltrimethylammonium methyl sulphate is a quaternary ammonium compound, also known as DTAC or DTTMS. It is an organic salt and classified as a cationic surfactant. The molecular formula of DTAC is C25H54NCH3SO4, and its formula weight is 507.79 g/mol. The CAS number for DTAC is 81646-13-1.
DTAC has various applications in the field of cosmetics, drug delivery systems, and pharmaceuticals. It is used as a preservative, emulsifier, and antimicrobial agent in several cosmetic products. In this article, we will explore the different aspects of DTAC, including health benefits, potential effects, product mechanism, safety, side effects, and dosing information.
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Other synonyms for DTAC include Docosyltrimethylammonium Methylsulfate, N,N-Docosyl-N,N-dimethyl-1-propanaminium methyl sulfate, and Trimethyl(docosyl)ammonium methyl sulfate.
Health Benefits of DTAC:
DTAC has several health benefits due to its antimicrobial properties. It is effective against a wide range of microorganisms, including bacteria, fungi, and viruses. DTAC disrupts the cell membrane of microorganisms, leading to their death.
DTAC is commonly used in pharmaceuticals to improve the efficacy of drug delivery systems. It enhances the absorption of drugs by increasing their solubility and stability. DTAC also enhances the penetration of drugs through the skin.
Potential Effects:
DTAC has several potential effects, both positive and negative. Its antimicrobial properties make it useful in preventing infections and preserving cosmetic products. It is also effective in improving the absorption of drugs, which can lead to more effective treatments. However, overuse of DTAC can lead to resistance among microorganisms, making it less effective over time.
Product Mechanism:
DTAC works by disrupting the cell membrane of microorganisms. It is attracted to the negatively charged surface of the cell membrane, where it binds to the phospholipid head groups. This leads to the disruption of the lipid bilayer, causing leakage of cellular contents and ultimately the death of the microorganism.
Safety:
DTAC is generally considered safe when used in appropriate amounts. However, excessive use can lead to skin irritation, allergic reactions, and respiratory problems. DTAC should not be ingested or applied to open wounds.
Side Effects:
The most common side effect of DTAC is skin irritation. This can manifest as redness, itching, and swelling. In rare cases, DTAC can cause allergic reactions, including hives, difficulty breathing, and anaphylaxis. If these symptoms occur, medical attention should be sought immediately.
Dosing Information:
DTAC is used in a variety of concentrations, depending on its intended application. For cosmetic products, DTAC is typically used at concentrations of 0.5-5%. Higher concentrations may cause skin irritation. In drug delivery systems, the concentration of DTAC varies depending on the specific drug being delivered.
Conclusion:
Docosyltrimethylammonium methyl sulphate is a versatile compound with numerous applications in cosmetics, drug delivery systems, and pharmaceuticals. Its antimicrobial properties make it effective in preventing infections and preserving cosmetic products. DTAC enhances the absorption of drugs, making them more effective. While generally safe when used appropriately, excessive use can lead to skin irritation and allergic reactions. As with any chemical compound, caution should be exercised when handling DTAC, and appropriate safety measures should be taken.