Galanthamine Hydrobromide (CAS: 1953-04-4) is a natural alkaloid extracted from the bulbs of Galanthus nivalis, commonly known as Snowdrop. It has been used for centuries as a traditional herbal medicine for various ailments, including memory impairment and cognitive disorders. Today, it is widely used as a therapeutic agent for the treatment of Alzheimer's disease and other forms of dementia. In this article, we will explore the chemical properties, health benefits, potential effects, safety, dosing information, and other important aspects of Galanthamine Hydrobromide.
Chemical name:
(4aS,6R,8aS)-5,6,9,10-tetrahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide
Molecular formula:
C17H21NO3・HBr
Formula weight:
368.27 g/mol
CAS No:
1953-04-4
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Health benefits of this product:
Galanthamine Hydrobromide is primarily used for treating Alzheimer's disease and other forms of dementia. It works by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine in the brain. By slowing down this process, Galanthamine Hydrobromide increases the amount of acetylcholine available in the brain, improving cognitive function and memory. Studies have shown that Galanthamine Hydrobromide can improve cognitive function in people with mild to moderate Alzheimer's disease and vascular dementia. It may also be beneficial for improving attention span and executive function in healthy individuals.
Potential effects:
Galanthamine Hydrobromide can improve memory and cognitive function in people with mild to moderate Alzheimer's disease and other forms of dementia. It may also help delay the progression of the disease and relieve some of the symptoms associated with dementia, such as confusion and agitation. Additionally, it may be useful for improving attention span and executive function in healthy individuals. Galanthamine Hydrobromide has also been studied for its potential use in treating other conditions, such as myasthenia gravis, a neuromuscular disease that causes muscle weakness and fatigue.
Product mechanism:
Galanthamine Hydrobromide works by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine in the brain. By slowing down this process, Galanthamine Hydrobromide increases the amount of acetylcholine available in the brain, improving cognitive function and memory.
Safety:
Galanthamine Hydrobromide is generally safe when taken as directed. However, like all medications, it can cause side effects in some people. Common side effects include nausea, vomiting, diarrhea, dizziness, headache, and loss of appetite. Serious side effects are rare but can include seizures, hallucinations, and heart rhythm disturbances. Galanthamine Hydrobromide should not be used in people with severe liver or kidney disease, stomach ulcers, or asthma. It should also be used with caution in people with heart problems or a history of seizures.
Dosing information:
The recommended dose of Galanthamine Hydrobromide for treating Alzheimer's disease and other forms of dementia is typically 16-24 mg per day, divided into two or three doses. The starting dose is usually 8 mg per day, gradually increasing over several weeks to the target dose. Doses should be taken with food to minimize gastrointestinal side effects.
Conclusion:
Galanthamine Hydrobromide is a natural alkaloid extracted from the bulbs of Galanthus nivalis, commonly known as Snowdrop. It is primarily used for treating Alzheimer's disease and other forms of dementia, where it can improve cognitive function and memory by inhibiting the enzyme acetylcholinesterase. Galanthamine Hydrobromide is generally safe when taken as directed, but it can cause side effects in some people. Overall, it is a promising therapeutic agent for the treatment of Alzheimer's disease and other forms of cognitive decline, and further research is needed to fully understand its potential benefits and risks.
