Lenalidomide-5-aminomethyl hydrochloride is a derivative of thalidomide and is used as an immunomodulatory drug in the treatment of hematological malignancies. It is a highly potent and selective inhibitor of tumor cell proliferation and angiogenesis, making it an attractive candidate for the treatment of multiple myeloma, mantle cell lymphoma, and other hematological tumors. The chemical formula of Lenalidomide-5-aminomethyl hydrochloride is C_13H_14N_4O_2·HCl and its molecular weight is 300.74 g/mol.
Chemical Name:
The chemical name of Lenalidomide-5-aminomethyl hydrochloride is 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione monohydrochloride.
CAS No:
The CAS number of Lenalidomide-5-aminomethyl hydrochloride is 1158264-69-7.
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Health Benefits of this Product:
Lenalidomide-5-aminomethyl hydrochloride has shown significant clinical benefits in the treatment of hematological malignancies. It works by inhibiting the growth of tumor cells and preventing the formation of new blood vessels that feed the tumors. It also activates the immune system to attack cancer cells. Studies have shown that Lenalidomide-5-aminomethyl hydrochloride can increase survival rates, delay disease progression, and improve quality of life in patients with multiple myeloma and mantle cell lymphoma.
Potential Effects:
Lenalidomide-5-aminomethyl hydrochloride is primarily used as an antineoplastic agent in the treatment of hematological malignancies such as multiple myeloma and mantle cell lymphoma. It works by inducing apoptosis (programmed cell death) in tumor cells, inhibiting angiogenesis (the formation of new blood vessels), and enhancing the immune response against cancer cells. Lenalidomide-5-aminomethyl hydrochloride has also been studied for its potential use in the treatment of various solid tumors, autoimmune diseases, and other conditions.
Product Mechanism:
Lenalidomide-5-aminomethyl hydrochloride works through multiple mechanisms to induce tumor cell death and inhibit angiogenesis. It binds to cereblon, a protein involved in regulating cellular processes, which in turn leads to the degradation of two proteins, Ikaros and Aiolos. This results in the activation of T cells and natural killer cells, which attack tumor cells. Lenalidomide-5-aminomethyl hydrochloride also inhibits the production of pro-inflammatory cytokines and stimulates the production of anti-inflammatory cytokines, which helps to reduce inflammation associated with cancer.
Safety:
Lenalidomide-5-aminomethyl hydrochloride is generally safe when used as directed under medical supervision. However, like all medications, it can cause side effects. Common side effects of Lenalidomide-5-aminomethyl hydrochloride include fatigue, nausea, diarrhea, constipation, and low white blood cell count. Rare but serious side effects may include blood clots, heart attack, stroke, and secondary malignancies. Patients should be monitored closely for these potential adverse effects.
Side Effects:
Although Lenalidomide-5-aminomethyl hydrochloride is generally well-tolerated, it can cause some side effects. These include fatigue, nausea, diarrhea, constipation, and low white blood cell count. In rare cases, Lenalidomide-5-aminomethyl hydrochloride can cause more serious side effects, such as blood clots, heart attack, stroke, and secondary cancers. Patients should be monitored closely for these potential adverse effects.
Dosing Information:
The recommended dose of Lenalidomide-5-aminomethyl hydrochloride varies depending on the condition being treated and the patient's individual needs. It is usually taken orally once daily, with or without food. The dose may be adjusted based on the patient's response to treatment and any side effects experienced. Patients should follow their doctor's instructions regarding dosing and take the medication exactly as prescribed
