Lycorine hydrochloride is a chemical compound that has been used for various purposes in the pharmaceutical and agricultural industries. This article aims to provide an overview of Lycorine hydrochloride, including its chemical properties, health benefits, potential effects, product mechanism, safety, side effects, dosing information, and conclusion.
Chemical Properties: Chemical name: (3S,4R)-9-Methoxy-7H-[1,3]dioxolo[4,5-g]quinolin-7-one hydrochloride Molecular formula: C16H15NO4.HCl Formula weight: 327.76 g/mol CAS No: 2188-68-3
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Synonyms: (−)-Lycorine hydrochloride; 1,2,3,9-Tetrahydro-9-methoxy-2,3-bis(methylene)-7H-benzol[s]-[1,3]dioxolo[4,5-g][quinoline-7-one] hydrochloride; (3S,4R)-7-Hydroxy-9-methoxy-7H-[1,3]dioxolo[4,5-g]quinolin-7-one hydrochloride; Narciclasine hydrochloride; Narcissidine hydrochloride
Health Benefits: Lycorine hydrochloride is known for its various health benefits due to its potent biological activity. It exhibits antiviral, antimicrobial, and anticancer properties. It can also be used as an angiogenesis inhibitor, which means it can prevent the growth of new blood vessels that are essential for tumor growth.
Anticancer Activity: Lycorine hydrochloride has shown significant anticancer activity against a variety of cancer cell lines, including leukemia, lung, colon, and breast cancer cells. It induces apoptosis, cell cycle arrest, and autophagy in cancer cells. It also inhibits the proliferation of cancer cells by suppressing various signaling pathways involved in tumor growth.
Antiviral Activity: Lycorine hydrochloride shows broad-spectrum antiviral activity against many viral strains, including HIV, hepatitis B and C viruses, influenza virus, and herpes simplex virus. It acts by inhibiting viral replication and entry into host cells.
Antimicrobial Activity: Lycorine hydrochloride has potent antimicrobial activity against various pathogenic bacteria and fungi. It can be used to treat various diseases caused by these microorganisms.
Potential Effects: Apart from its health benefits, Lycorine hydrochloride also exhibits several potential effects, such as:
Anti-inflammatory Activity: Lycorine hydrochloride has anti-inflammatory activity, which means it can reduce inflammation and swelling caused by various inflammatory diseases.
Neuroprotective Activity: Lycorine hydrochloride exhibits neuroprotective activity, which means it can protect neurons from damage and prevent neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Cardioprotective Activity: Lycorine hydrochloride exhibits cardioprotective activity, which means it can protect the heart from damage and prevent cardiovascular diseases such as myocardial infarction.
Product Mechanism: The exact mechanism of how Lycorine hydrochloride works is not fully understood. However, studies have shown that it can inhibit various signaling pathways involved in cell growth, proliferation, and survival. It can also induce apoptosis, cell cycle arrest, and autophagy in cancer cells. Lycorine hydrochloride also exhibits antiviral activity by inhibiting viral replication and entry into host cells.
Safety: Lycorine hydrochloride is generally safe when used in recommended doses. However, it can cause side effects when taken in larger doses. Therefore, it is recommended to consult a healthcare provider before using this product.
Side Effects: Some of the common side effects of Lycorine hydrochloride include:
Nausea Vomiting Diarrhea Abdominal pain Headache Dizziness Fatigue
Dosing Information: The appropriate dose of Lycorine hydrochloride depends on several factors such as age, health condition, and other medications being taken. Therefore, it is recommended to consult a healthcare provider before using this product.