Pemetrexed disodium hemipentahydrate, also known as Alimta, is a chemotherapy drug that is used to treat mesothelioma, non-small cell lung cancer, and other types of cancer. It was first approved by the FDA in 2004 and has since become a widely used treatment option for cancer patients. In this article, we will explore the properties, benefits, and potential side effects of pemetrexed disodium hemipentahydrate.
Chemical name:
The chemical name of pemetrexed disodium hemipentahydrate is disodium [[(2R)-2-[[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-4-methylpentanoyl]amino]methanesulfonate hemipentahydrate.
Molecular formula:
The molecular formula of pemetrexed disodium hemipentahydrate is C20H19N5Na2O6S·2.5H2O.
Formula weight:
The formula weight of pemetrexed disodium hemipentahydrate is 597.49 g/mol.
CAS No:
The CAS number for pemetrexed disodium hemipentahydrate is 357166-30-4.
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Health benefits of pemetrexed disodium hemipentahydrate:
Pemetrexed disodium hemipentahydrate is an effective chemotherapy drug that has been shown to improve survival rates in patients with mesothelioma and non-small cell lung cancer. It works by inhibiting the growth of cancer cells, preventing them from replicating and spreading throughout the body.
Potential effects:
Pemetrexed disodium hemipentahydrate can cause a range of potential effects, including nausea, vomiting, fatigue, hair loss, and decreased appetite. It may also cause more serious side effects, such as low white blood cell count, increased risk of infection, and kidney damage. Patients who experience any adverse effects should consult with their healthcare provider immediately.
Product mechanism:
Pemetrexed disodium hemipentahydrate works by blocking several enzymes that are involved in the formation of DNA and RNA in cancer cells. By doing so, it stops the growth and spread of cancer cells. It is typically administered intravenously and is often given in combination with other chemotherapy drugs.
Safety:
Pemetrexed disodium hemipentahydrate is generally considered safe when used under the guidance of a healthcare professional. However, it can cause serious side effects, such as low white blood cell count, that may require medical attention. Patients should always inform their healthcare provider of any existing medical conditions or medications they are taking before starting treatment with pemetrexed disodium hemipentahydrate.
Side effects:
The most common side effects of pemetrexed disodium hemipentahydrate include nausea, vomiting, fatigue, hair loss, and decreased appetite. More serious side effects may occur, such as low white blood cell count, increased risk of infection, and kidney damage. Patients should discuss potential side effects with their healthcare provider before starting treatment.
Dosing information:
The dosing of pemetrexed disodium hemipentahydrate will vary depending on the type of cancer being treated and the patient's overall health. The drug is typically administered intravenously and is often given in combination with other chemotherapy drugs. Patients should follow their healthcare provider's instructions regarding dosing and administration of pemetrexed disodium hemipentahydrate.
Conclusion:
Pemetrexed disodium hemipentahydrate is an effective chemotherapy drug that is used to treat mesothelioma, non-small cell lung cancer, and other types of cancer. While it can cause side effects, it has been shown to improve survival rates in patients with these types of cancer. Patients who are considering treatment with pemetrexed disodium hemipentahydrate should discuss potential benefits and risks with their healthcare provider to determine if it is the best treatment option for them.
