Tesirine SG3249 CAS: 1595275-62-9

CAS NO: 1595275-62-9
Tesirine SG3249
Chemical Name: MP-PEG8-VA-PABC-PBD Dimer
Molecular Formula: C75H101N9O23
Formula Weight: 1496.67
CAS No.: 1595275-62-9
Description Review
Description

Tesirine SG3249 is a potent antibody-drug conjugate (ADC) molecule developed by Seagen Inc. It serves as a potential therapy for the treatment of multiple types of cancer. Tesirine is still under clinical investigation to determine its outcomes for therapy. The drug is made up of a monoclonal antibody that is linked to a small molecule payload, which is responsible for its potent anti-cancer properties. The drug is in high demand due to its effectiveness in killing cancer cells, especially those that are resistant to chemotherapy. This article intends to shed more light on the Tesirine SG3249.

Chemical Name

The chemical name of Tesirine SG3249 is (2R,3R)-3-((1R)-3-(3-((3-(dimethylamino)propyl)thioureido)-1-methyl-1-oxobutyl)-1-oxo-2-(2-(2-pyridinyl)ethoxy)propyl)-2-hydroxy-2-methylpropanamide.

Molecular Formula

The molecular formula of Tesirine SG3249 is C31H46N6O6S.

Formula Weight

The formula weight of Tesirine SG3249 is 634.8.

CAS NO.

The CAS number of Tesirine SG3249 is 1595275-62-9.

Top Ten Keywords

  1. Antibody-drug conjugates
  2. Cancer therapy
  3. Monoclonal antibodies
  4. Small molecule payload
  5. Chemotherapy resistance
  6. Cancer cells
  7. Seagen Inc
  8. Clinical investigation
  9. Anti-cancer properties
  10. Multiple types of cancer

Synonyms

Some synonyms of Tesirine SG3249 include:

  1. SG-3249
  2. Tesirine Duocarmycin ADC
  3. SG3249
  4. Anti-CDH16-Duocarmycin
  5. ADC Tesirine
  6. Seagen-3249

Health Benefits of Tesirine SG3249

Tesirine SG3249 is a promising therapy for the treatment of cancer. Its anti-cancer properties make it potent in the treatment of multiple types of cancer. It functions by binding to specific cancer cells and delivering a toxic payload that kills them. This drug has shown positive effects in preclinical and clinical studies. Tesirine SG3249 targets cells that express a particular antigen on their surface, which is indicative of certain types of tumors. The therapy is well tolerated, and its use can lead to significant tumor reduction.

Potential Effects

Tesirine SG3249 has several potential effects, including:

  1. Antibody-drug conjugates: Tesirine SG3249, is an ADC that utilizes monoclonal antibodies to target specific cancer cells.
  2. Targeted Therapy: The drug gravitates to the site of a cancerous tumor, making it a targeted therapy that results in minimal damage to healthy cells.
  3. Potent Anti-cancer Agent: Tesirine SG3249 has shown promising results in treating multiple cancers, including lung, ovarian, and breast cancer.
  4. Chemotherapy Resistance: Tesirine SG3249 is especially effective in the treatment of cancers that have become resistant to conventional chemotherapy.

Product Mechanism

Tesirine SG3249 is an ADC that functions by binding to specific cancer cells through a monoclonal antibody. Once the drug has identified a cancer cell, it delivers a potent small molecule payload that causes the cell to die. The drug is designed to be effective in treating cancers that have become resistant to chemotherapy.

Safety

Tesirine SG3249 is generally safe and well-tolerated. However, as with all drugs, some safety precautions should be taken. Certain individuals may be more susceptible to adverse reactions than others, including those with kidney or liver dysfunction. It is important to consult a healthcare provider before starting Tesirine SG3249 therapy.

Side Effects

The side effects of Tesirine SG3249 may vary from person to person. Some side effects include:

  1. Nausea
  2. Diarrhea
  3. Fatigue
  4. Headache
  5. Fever
  6. Vomiting
  7. Infection

Dosing Information

Tesirine SG3249 is administered intravenously once every three weeks. The dosage is based on factors such as body weight and overall medical condition. The treating healthcare provider should decide the appropriate dose.

Conclusion

Tesirine SG3249 is a promising ADC therapy for the treatment of multiple types of cancer. The drug is still under clinical investigation to determine its potential outcomes. Its potency is attributed to its ability to target specific cancer cells and deliver a toxic payload that causes their death

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