Tetramisole hydrochloride, also known as Levamisole hydrochloride or anthelminthic agent 52, is an organic compound with the chemical formula C11H12N2S•HCl and a molecular weight of 240.75 g/mol. It is a white crystalline powder that is commonly used as an anthelmintic agent to treat parasitic infections in animals. The CAS number for this compound is 5086-74-8.
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Health Benefits of Tetramisole Hydrochloride Tetramisole hydrochloride is primarily used as an anthelmintic agent to treat parasitic infections in animals. In addition, it has been studied for its potential immunomodulatory effects in humans, particularly in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus.
Potential Effects of Tetramisole Hydrochloride Tetramisole hydrochloride acts as an inhibitor of acetylcholinesterase, an enzyme involved in the transmission of nerve impulses. As an anthelmintic agent, it works by paralyzing and killing parasitic worms, such as roundworms and hookworms. In humans, it has been shown to have potential immunomodulatory effects, potentially reducing inflammation and regulating immune function.
Product Mechanism Tetramisole hydrochloride works by inhibiting acetylcholinesterase, leading to an accumulation of acetylcholine at neuromuscular junctions in parasitic worms. This results in paralysis and eventual death of the parasite. In humans, tetramisole hydrochloride has been shown to modulate immune function by regulating T-cell activity and cytokine production.
Safety Tetramisole hydrochloride is generally safe when used as directed in veterinary medicine. However, it should not be used in pregnant or lactating animals, and caution should be exercised when administering to animals with liver or kidney disease. In humans, tetramisole hydrochloride should only be used under the supervision of a qualified healthcare professional.
Side Effects In animals, side effects of tetramisole hydrochloride may include vomiting, diarrhea, and loss of appetite. In rare cases, severe allergic reactions may occur. In humans, side effects may include nausea, vomiting, diarrhea, abdominal pain, dizziness, and headache. In rare cases, serious adverse events such as agranulocytosis and vasculitis have been reported.
Dosing Information The recommended dosage of tetramisole hydrochloride varies depending on the type of animal being treated and the severity of the parasitic infection. It should only be administered by a licensed veterinarian or healthcare professional. In humans, dosing should be determined by a qualified healthcare professional and based on individual factors such as age, weight, and medical history.
Conclusion In conclusion, tetramisole hydrochloride is primarily used as an anthelmintic agent to treat parasitic infections in animals. It has also been studied for its potential immunomodulatory effects in humans. Although generally safe when used as directed, caution should be exercised when administering tetramisole hydrochloride to animals or humans, and it should only be used under the guidance of a qualified healthcare professional.
