VB124 MCT4 Inhibitor is a ground-breaking therapeutic compound that presents an exciting opportunity for cancer treatment. MCT4 is one of the promising targets for cancer therapy that inhibits the efflux of lactate, a process that helps in the survival and growth of cancerous cells. VB124 acts as a non-competitive inhibitor of MCT4, which in turn suppresses glycolytic activity. This leads to a reduction in lactate extrusion and, subsequently, inhibition of tumor growth.
Chemical Name
The chemical name of VB124 MCT4 Inhibitor is [(5-(phenylmethoxy)pyrimidin-2-yl)amino]-(2-(2-(5-(trifluoromethyl)pyrimidin-2-yl)hydrazin-1-ylidene)acetyl)amine.
Molecular Formula
The molecular formula of VB124 MCT4 Inhibitor is C22H18F3N7O.
Formula Weight
The formula weight of VB124 MCT4 Inhibitor is 459.43 g/mol.
CAS No
The CAS Number of VB124 MCT4 Inhibitor is 2230186-18-0.
Top Ten Keywords from Google and Synonyms
Synonyms:
Health benefits of this product
VB124 MCT4 Inhibitor has numerous health benefits, including its potential to inhibit tumor growth. The compound works by blocking the efflux of lactate, which is an essential nutrient for the survival and growth of cancer cells. By inhibiting lactate export, VB124 can target the MCT4 protein's activity, which is responsible for lactate export.
Potential Effects
VB124 MCT4 Inhibitor can be a useful adjunct therapy for cancer patients. By suppressing glycolytic activity, the compound can reduce lactate extrusion, resulting in the inhibition of tumor growth. In preclinical studies, it has been shown to display potent anticancer activity in glioma cells, and its effectiveness against other types of cancer cells is also being studied.
Product Mechanism
VB124 MCT4 Inhibitor acts by inhibiting the function of MCT4 protein, responsible for lactate export. The Warburg effect describes the high glycolysis rate present in cancer cells, which produces excess lactate. MCT4 plays a crucial role in the Warburg effect by effluxing lactate out of cells. VB124 inhibits this process, leading to a buildup of lactate in the cells, and ultimately inhibiting their survival and growth.
Safety
VB124 MCT4 Inhibitor is a relatively safe therapeutic compound. In preclinical studies, it has been shown to be well-tolerated with a favorable safety profile.
